摘要
目的对浙江省居民经黄酒中摄入氨基甲酸乙酯进行初步评估,分析其摄入对健康损害的风险。方法利用2008年全省18岁及以上人群黄酒消费量调查数据,以及2010年、2011年和2012年采集黄酒样品中氨基甲酸乙酯的检测结果,采用简单分布膳食暴露评估方法对人群经黄酒摄入氨基甲酸乙酯进行估计,并对造成的健康风险进行评估。结果 2010年、2011年和2012年采集黄酒中氨基甲酸乙酯的平均含量分别为0.100 mg/kg、0.103 mg/kg和0.116 mg/kg,最大值分别为0.430 mg/kg、0.450 mg/kg和0.458 mg/kg。18岁以上一般人群黄酒氨基甲酸乙酯平均暴露量分别为24.5 ng/(kg·bw)、25.2 ng/(kg·bw)和28.4 ng/(kg·bw),暴露限值分别为12 245、11 905和10 563。结论 18岁及以上全部人群黄酒氨基甲酸乙酯暴露的健康风险较低。
Objective To perform exposure assessment of dietary ethyl carbamate（ EC） in rice wine for residents of Zhejiang,and to analyze its intake risks on human health. Methods The simple distribution method was introduced in dietary exposure assessment of ethyl carbamate derived from rice wine consumed by population aged 18 and above. Subsequently,their health risk assessment was conducted. The consumption data of rice wine from dietary survey in Zhejiang（ 2008） and the ethyl carbamate concentrate data from the survey in 2010,2011 and 2012 respectively were adopted in dietary exposure assessment.Results The mean and the maximum values of ethyl carbamate in rice wine sample were 0. 100 mg/kg and 0. 430 mg/kg,0. 103 mg/kg and 0. 450 mg/kg,0. 116 mg/kg and 0. 458 mg/kg in 2010,2011 and 2012,respectively. The average intake of ethyl carbamate and the margin of exposure（ MOE） value among population aged 18 and above were 24. 5 ng/（ kg·bw） and12 245,25. 2 ng/（ kg·bw） and 11 905,28. 4 ng/（ kg·bw） and 10 563. Conclusion For the population aged 18 and above in Zhejiang,the health risk caused by ethyl carbamate intake from rice wine was quite low.
作者
陈江
吴平谷
张荷香
齐小娟
周标
章荣华
CHEN Jiang WU Ping- gu ZHANG He- xiang QI Xiao-juan ZHOU Biao ZHANG Rong- hua(Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang 310051, China)
出处
《中国卫生检验杂志》
CAS
2017年第1期11-13,共3页
Chinese Journal of Health Laboratory Technology
基金
浙江省重点科技创新团队计划资助(2011R50021)
浙江省医药卫生科技项目(2016ZHB007)
关键词
氨基甲酸乙酯
黄酒
暴露评估
浙江省
Ethyl carbamate
Rice wine
Exposure assessment
Zhejiang province
