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伴高同型半胱氨酸的高血压患者靶器官损害的分析

Analysis of Target Organ Damage in Hypertension with Hyperhomocysteine
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摘要 目的分析伴高血同型半胱氨酸血症的高血压患者的靶器官损害的情况。方法对43例血同型半胱氨酸大于15mmol/L的高血压患者和72例血同型半胱氨酸正常的高血压患者行高血压靶器官的评估,比较两组间颈动脉粥样硬化、高血压心肌重塑、高血压性视网膜病变、尿蛋白及总靶器官损害的阳性检出率。结果伴高同型半胱氨酸高血压患者组颈动脉粥样硬化及总靶器官损害的阳性检出率明显高于对照组,且有正相关性(r=0.196,r=0.203,P〈0.05),但其余靶器官损害两组间无差异。结论高血压患者中,伴血同型半胱氨酸增高的高血压患者颈动脉粥样硬化更易发生。 Objective To analsize the condition of target organ damage in hypertension with hyperhomocysteine. Methods All hypertensives were divided into two groups : 43 case with hyperhomocysteine and 72 case were normal homocysteine, then were compared the positive screening of carotid artery artherosclerosis, Cardiac remodeling, retinopathy and Urine protein between two groups, Results 1. the positive screening of carotid artery artheroselerosis and total target organs damage in H hypertension group was significant higher than control group. (P〈0. 05) 2. There was positive correlation between H type hypertension and carotid artery artherosclerosis and total target organs damage(r=0. 196,r=0. 203, P〈0.05). Conclusion Comparing with other target organ damage,there was a correlation between Hypertensives with Hyperhomocysteine and carotid artery artherosclerosis.
出处 《检验医学》 CAS 2016年第B09期101-102,共2页 Laboratory Medicine
基金 新疆维吾尔自治区人民医院院内科研项目(20130310)
关键词 高血压 同型半胱氨酸 靶器官损害 hypertension homocysteine target organ damage
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