摘要
目的分析急性重症胰腺炎早期连续性肾脏替代疗法(CRRT)的治疗效果。方法选择我院收治的急性重症胰腺炎患者120例,按照病历号将患者分为两组,每组60例。对照组患者采用临床常规综合性保守疗法,试验组患者在对照组的基础上联合CRRT治疗,比较两组患者的治疗效果及死亡率,并检测两组患者治疗后血中的细胞因子水平。结果试验组患者的治疗总有效率明显高于对照组,死亡率明显低于对照组(P<0.05);治疗后,试验组患者的血淀粉酶、白细胞介素-1、肿瘤坏死因子-α水平均明显低于对照组(P<0.05)。结论 CRRT治疗急性重症胰腺炎具有显著的临床效果,对促进患者康复、提高患者的生活质量具有重要意义。
Objective To analyze the clinical effect of early continuous renal replacement therapy （CRRT） in patients with acute severe pancreatitis. Methods One hundred and twenty patients with acute severe pancreatitis admitted in our hospital were divided into two groups according to the patient record number, with 60 case in each group. The control group was treated with routine clinical comprehensive conservative treatment, while the experimental group accepted CRRT treatment on the basis of the control group. The clinical therapeutic effect and mortality rate of the two groups were compared and the levels of cytokines in the blood of the two groups were measured. Results The total effective rate of the experimental group was significantly higher than that in the control group, the mortality rate was significantly lower than that in the control group （P〈0.05）. After treatment, the levels of serum amylase, interleukin-1 and tumor necrosis factor-α in the experimental group were significantly lower than those in the control group （P〈0.05）. Conclusion CRRT has significant clinical effect in the treatment of acute severe pancreatitis, which has an important significance for promoting the rehabilitation of patients and improving the quality of life of patients.
出处
《临床医学研究与实践》
2017年第3期44-45,共2页
Clinical Research and Practice
关键词
连续性肾脏替代
急性重症胰腺炎
血淀粉酶
continuous renal replacement therapy
acute severe pancreatitis
serum amylass
