摘要
目的探讨双歧杆菌三联活菌治疗抗生素相关性腹泻的疗效。方法选择临床诊断为抗生素相关性腹泻的130例患儿，根据用药方法的不同分成治疗组（65例）和对照组（65例）。治疗组口服双歧杆菌三联活菌，对照组口服蒙脱石散剂，疗程3天。观察临床治疗效果。结果治疗组脱落5例，对照组脱落5例。治疗组临床显效率、总有效率分别为80．00％、100．00％，对照组分别为56．67％、90．00％，两组比较差异均有统计学意义（P〈0．01或P〈0．05），平均止泻时间治疗组（2．83±0．64）d，对照组（3．57±0．92）d，两组比较差异有统计学意义（P〈0．01）。结论双歧杆菌三联活菌治疗抗生素相关性腹泻疗效显著，安全可靠，具有较高的临床应用价值。
Objective To discuss curative efficacy of bifid triple viable in treatment of patients with antibiotic associated diarrhea （AAD）. Methods 130 pediatric patients with AAD were randomly divided into two groups. Patients in therapy group（65）were administered with bifid triple viable and in control group（65）with Smectite Powder. All the treatments lasted for 3 days. And the two groups were compared in their therapeutic effects and the duration of diarrhea. Results Five patients lost to follow-up in therapy group and 5 in the control group. Total effective rate of therapy group＇s was 100.00% and control group＇s was 90.00%. There was a statis＂ tic difference between two groups （P 〈 0.01 or P 〈 0.05）. And there was also a statistic difference in curative rate between two groups（80.00% vs. 56.67%,P 〈 0.01）. The days of diarrhea in therapy group were （2.83 ± 0.64） d and the control group were （3.57± 0.92） d, and there was a statistic difference（P 〈 0.01）. Conclusions Bifid triple viable is a safe and highly effective probiotics in the treatment of AAD for children, and it is worthy of application.
作者
吴启富
陈青松
Wu Qifu Chen Qingsong(The Material and Children Health Hospital, Huaying 638600, Sichuan, Chin)
出处
《医院与医学》
2017年第1期67-70,共4页
Hospital and Medicine
