摘要
目的：探讨早期宫颈腺癌卵巢转移的危险因素，为早期宫颈腺癌患者保留卵巢功能提供决策依据。方法回顾性分析111例早期宫颈腺癌（Ⅰa2-Ⅱa 期）患者的临床病理资料，分析其卵巢转移的危险因素。结果111例早期宫颈腺癌患者中，发生卵巢转移9例，转移率8.1％；临床分期、肿瘤直径、宫旁受侵、淋巴结转移、肌层浸润深度、病理分级、宫体受侵及输卵管转移与卵巢转移有关（P ﹤0.05）；Logistic 回归分析显示：肿瘤大小、宫旁侵犯及输卵管转移与卵巢转移相关（P ﹤0.05）。结论对于早期宫颈腺癌患者，保留卵巢存在一定风险，但对于没有高危因素的早期宫颈腺癌患者，特别是强烈希望保留卵巢功能的年轻患者，充分与患者沟通后可考虑保留卵巢。
Objective To analyze the risk factors for ovarian metastasis from early cervical adenocarcinoma,to provide a basis for preserving ovarian function in the patients with early cervical adenocarcinoma. Methods The clinicopathologic data of 111 patients with early cervical adenocarcinoma were analyzed retrospectively. The risk fac-tors of ovarian metastasis were subjected. Results Among the 111 patients with early cervical adenocarcinoma （stage Ⅰa2 and Ⅱa）,9 patients had ovarian metastasis and the transfer rate was 8. 1% . The Pearson Chi square test showed that ovarian metastasis was related to the clinical stage,palace metastasis,oviduct,deep myometrial inva-sion,tumor size,pathological grading,uterine body invasion and pelvic lymph node metastasis（P ﹤ 0. 05）. Logistic regression analysis showed that ovarian metastasis was related to the tumor size,palace metastasis and oviduct metas-tasis（P ﹤ 0. 05）. Conclusion There are some risks for early cervical adenocarcinoma;the risk factors for ovarian metastasis from young patients who want to keep ovaries must be carefully assessed.
出处
《肿瘤基础与临床》
2016年第4期335-337,共3页
journal of basic and clinical oncology
关键词
宫颈腺癌
卵巢转移
危险因素
cervical adenocarcinoma
ovarian metastasis
risk factors
