摘要
A new hexaketide acid esterified by the 17-hydroxyl group of 16,17-dihydroxycyclooctatin, namely 17-[16,17-dihydroxycyclooctatinyl]-hexaketide ester(1), a member of the group of rare bacterial diterpenes with a fused 5-8-5 ring system was isolated from strain Streptomyces sp. SR107. The structure was determined on the basis of its spectral data(~1H NMR, ^(13) C NMR, ~1H-~1H COSY, HSQC, HMBC, NOESY, IR and HR-ESI-MS). The antibacterial activity was also evaluated in this paper.
A new hexaketide acid esterified by the 17-hydroxyl group of 16,17-dihydroxycyclooctatin, namely 17-[16,17-dihydroxycyclooctatinyl]-hexaketide ester（1）, a member of the group of rare bacterial diterpenes with a fused 5-8-5 ring system was isolated from strain Streptomyces sp. SR107. The structure was determined on the basis of its spectral data（~1H NMR, ^（13） C NMR, ~1H-~1H COSY, HSQC, HMBC, NOESY, IR and HR-ESI-MS）. The antibacterial activity was also evaluated in this paper.
基金
supported in part by National Basic Research Programs of China(No.2012CB721005)
the Natural Science Foundation of Shandong Province Youth Project(No.ZR2013 HQ048)
Program for Changjiang Scholars and Innovative Research Team in University(No.IRT13028)
