摘要
目的探讨胸腺瘤患者的生存状况，为提高胸腺瘤的生存状况提供科学依据。方法回顾性分析2005年1月至2010年12月住院并行手术治疗的胸腺瘤患者62例的临床资料，包括性别比例、年龄分布、是否伴随吸烟、是否伴随饮酒、手术方式、WHO组织学标准分类、肿瘤直径、是否合并重症肌无力、Latter／Bematz（L／B）组织学标准分类、Masaoka分期、侵犯程度，通过kaplan—meier检验确定相关影响因素，通过COX多因素分析确定胸腺瘤生存状况的独立影响因素。结果胸腺瘤患者的5年生存率为51．6％（32／62），单因素分析结果提示，手术方式、WHO组织学标准分类、Masaoka分期是胸腺瘤5年生存率的相关性因素；胸腺瘤患者的10年生存率为41．9％（26／62），性别、年龄分布、手术方式、WHO组织学标准分类、Masaoka分期是胸腺瘤患者10年生存率的相关性因素。手术方式和Masaoka分期是胸腺瘤患者5年生存率的独立影响因素；年龄、手术方式和Masaoka分期是胸腺瘤患者10年生存率的独立影响因素。结论胸腺瘤患者的手术方式和Masaoka分期是胸腺瘤患者5年生存率的独立影响因素，年龄、手术方式和Masaoka分期是胸腺瘤患者10年生存率的独立影响因素，为了进一步延长患者的生存时间，对于年龄〉50岁的患者、不能行完全切除肿瘤术的患者以及Masaoka分期属于Ⅲ期和Ⅳ期的患者要给予更加的重视和相关的措施。
scientific basis for lyzed the clinical Objective To investigate the survival status of patients with thymoma, and provide improving the living conditions of thymoma. Methods This study retrospectively ana-data of 62 cases of thymoma by surgical treatment from January 2005 to December 2010, including sex ratio, age distribution, whether associated with smoking, whether accompanied by drinking , surgery, WHO histological classification, tumor diameter, whether complicated with myasthe-nia gravis, Latter/Bematz （L/B） standard histological classification, Masaoka stage, invasion degree, through kaplan-meier analysis to identify the related factors, through COX multi factor analysis independ- ent factors determine the survival status of thymoma. Results Five years survival rate of patients with thymoma was 51.6% （32/62）, the single factor analysis showed that WHO surgery, histological classifi- cation, Masaoka stage was the 5 year survival rate of thymoma associated factors ; 10 years survival rate of thymoma patients was 41.9% （26/62）, gender, age distribution, operation mode, WHO standard histo-logical classification, Masaoka stage was the correlation factors of 10 years survival rate of patients with thymoma. Surgical approach and Masaoka staging were independent risk factors of the 5 years survival rate of patients with thymoma; age, surgery and Masaoka stage were independent factors affecting the l0 years survival rate of patients with thymoma. Conclusions The operation mode and Masaoka stage were independent factors affecting the survival rate of 5 years of thymoma patient; age, operation mode and Masaoka staging were independent factors affecting the survival rate of 10 years of thymoma patients, in order to further prolong the survival time of patients. For patients over 50 years old, patients who cannot complete resection of the tumor and Masaoka stage of stage Ⅲ and Ⅳ, we should be given more attention and related measures.
出处
《中国实用医刊》
2016年第23期48-51,共4页
Chinese Journal of Practical Medicine
关键词
胸腺瘤
生存状况
影响因素
Thymoma
Living condition
Influencing factors
