摘要
基底节钙化是一种少见的神经变性疾病，其病理改变主要为双侧基底节区钙化斑。患者大多以锥体外系症状为首发症状，还可表现为小脑功能失调、语言障碍、痴呆、癫痫和神经精神症状等，部分患者可终生无症状。基底节钙化目前尚无特效方法可治疗或延缓疾病进展，且药物大多数效果不佳或耐受性较差。该研究就其病因、发病机制、病理变化、影像学表现、临床特点及治疗方法做一综述。
The prevalence of basal ganglia calcification is increasing,and it is a rare neurodegenerative dis-ease.Its pathological changes are mainly bilateral basal ganglia calcification plaques.Most patients with pyramidal symptoms as the starting symptoms,but also manifested cerebellar dysfunction,language disorder,dementia,epilepsy and neurological symptoms,some patients can be asymptomatic.At present,there is no specific method to treat or delay the progress of the disease,and the majority of the drug effect is not good or poor tolerability.This article reviews the etiology,pathogenesis,pathological changes,imaging features,clinical features and treatment methods.
作者
张汉华
周烨威
周平
Zhang Hanhua Zhou Yewei Zhou Ping.(Department of Neurology, Jingmen Convalescent Hospital, Jingmen, Hubei 448000, Chin)
出处
《中国基层医药》
CAS
2016年第24期3822-3825,共4页
Chinese Journal of Primary Medicine and Pharmacy
关键词
脑血管基底神经节疾病
特发性
综合征
Basal ganglia cerebrovascular disease
Idiopathic
Syndrome
