摘要
目的探究2型糖尿病应用门冬胰岛素联合二甲双胍片治疗的临床疗效,探究其是否具有可靠的安全药用疗效,以及是否能够广泛应用于临床医学治疗中.方法将我院的50例确诊为2型糖尿病的患者用随机分配法分为两组,平均每组25人.设立观察组与对照组,观察组采用二型糖尿病应用门冬胰岛素联合二甲双胍片治疗,而对照组采用传统的2型糖尿病治疗手段.观察并记录治后疗效,根据结果得出研究结论.结果观察组在治疗前的空腹血糖、餐后两小时内的血糖以及糖化血红蛋白分别为（11.78±1.32）mmol/L、（18.43±1.56）mmol/L、（10.23±3.85）00,治疗后分别为（6.21±0.63）mmol/L、（8.56±1.04）mmol/L、（6.32±1.72）00;对照组在治疗前的空腹血糖、餐后两小时内的血糖以及糖化血红蛋白分别为（11.75±1.30）mmol/L、（18.37±1.62）mmol/L、（10.14±3.76）00,治疗后分别为（6.52±0.68）mmol/L、（9.45±1.34）mmol/L、（7.14±1.76）00.其中对照组与观察组两组发生的低血糖均为两例,胃肠道反应均为两例,不良反应发生率相同.结论门冬胰岛素联合二甲双胍片治疗2型糖尿病患者的治疗方法疗效好、安全性高,可以进行临床的推广,比一般的治疗2型糖尿病的治疗方法更具有疗效.
ObjectiveTo explore the clinical efficacy of insulin aspart combined with metformin tablets in the treatment of type 2 diabetes,to explore whether it has reliable safety and medical efficacy, and whether it can be widely used in clinical medicine treatment.Methods 50 patients diagnosed as type 2 diabetes in our hospital were randomly divided into two groups, with 25 in each group.Set up the observation group and control group and observation group with type ii diabetes used door winter insulin with metformin therapy, while the control group used the traditional treatment of type 2 diabetes.Observe and record after cure curative effect, according to the outcomings of research conclusions.ResultIn the observation group before treatment, fasting blood glucose, postprandial blood glucose and glycosylated hemoglobin were （11.78 ±1.32） L / mmol, （18.43 ±1.56） L / mmol, （10.23 ±3.85） 00 ,After treatment respectively, （6.21±0.63） L / mmol, （8.56 ±1.04） L / mmol, （6.32 ±1.72） 00 ;In the control group before treatment, fasting blood glucose, postprandial blood glucose and glycosylated hemoglobin were （11.75 ± 1.30） L / mmol, （18.37±1.62）L / mmol, （10.14 ± 3.76）00 , After treatment respectively, （6.52 ± 0.68） L / mmol, （9.45 ± 1.34） L / mmol, （7.14 ± 1.76） 00.Among them control group and observation group two groups of hypoglycemia are two cases, gastrointestinal reaction are two cases, the incidence of adverse reactions to the same.ConclusionDoor winter insulin with metformin therapy in patients with type 2 diabetes treatment good curative effect, high security, can undertake clinical promotion, than the general treatment of type 2 diabetes treatment has more effect.
出处
《湖南中医药大学学报》
CAS
2016年第A02期1025-1026,共2页
Journal of Hunan University of Chinese Medicine
