摘要
目的探讨血清和肽素、降钙素原及超敏C-反应蛋白在脑出血合并肺部感染患者早期诊断及预后判断中的应用价值,为临床治疗提供参考依据。方法选取2014年8月-2015年8月医院收治的急性脑出血患者98例,分为脑出血组65例,感染组33例,另选同期进行健康体检50名为对照组;比较3组受试者临床指标。结果与健康对照组相比,脑出血组、感染组患者血清和肽素、超敏C-反应蛋白水平明显提高,差异均有统计学(P<0.05);与脑出血组患者相比,感染组患者在发病后6h、24h和7d血清和肽素、降钙素原、超敏C-反应蛋白水平显著提高,差异均具有统计学意义(P<0.05)。结论血清和肽素、降钙素原及超敏C-反应蛋白对脑出血合并肺部感染患者的早期诊断以及预后的判断均具有十分重要的参考价值。
OBJECTIVE To discuss the application value of detection of copeptin,procalction and hypersensitivity Creactive protein in early diagnosis and prognosis of cerebral hemorrhage-associated pulmonary infections,so as to provide references for clinical treatment.METHODS From Aug.2014 to Aug.2015,98 patients with acute cerebral hemorrhage were selected in our hospital.The patients were divided into cerebral hemorrhage group（n=65）and infection group（n=33）,and 50 healthy examination persons in our hospital during the same period were selected as control group.The clinical indexes in the three groups were compared.RESULTS Compared with healthy control group,the levels of copeptin and hypersensitivity C-reactive protein in cerebral hemorrhage group and infection group were increased significantly（P〈0.05）.Compared with cerebral hemorrhage group,the levels of copeptin,procalction and hypersensitivity C-reactive protein in infection group after 6h,24 hand 7dwere increased significantly（P〈0.05）.CONCLUSIONDetection of copeptin,procalction and hypersensitivity C-reactive protein has very important reference value in early diagnosis and prognosis of cerebral hemorrhage-associated pulmonary infection.
作者
刘海玉
周国平
李东峰
马新强
谢强
LIU Hai-yu ZHOU Guo-ping LI Dong-feng MA Xin-qiang XIE Qiang(Affiliated Hospital of Zhengzhou University, Nanyang Central Hospital, Nanyang, Henan 473000, Chin)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第23期5410-5412,共3页
Chinese Journal of Nosocomiology
基金
河南省教育厅科学技术研究重点项目(142104510123)
关键词
脑出血
肺部感染
诊断
预后
Cerebral hemorrhage
Pulmonary infection
Diagnosis
Prognosis
