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骨关节炎的表观遗传学研究进展 被引量:2

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摘要 OA是一种最常见的关节炎,是导致中老年人群慢性残疾的主要原因。Carter等口认为OA主要发生在膝、髋等负重关节,一直被认为是力学因素所导致,同样徐卿荣等啾为生物学致病因子对正常关节软骨存在损害作用,但明显弱于力学因素。然而,近年来有越来越多的证据支持OA是由机械力学和分子事件间相互作用共同导致的关节受累。
出处 《中华风湿病学杂志》 CAS CSCD 北大核心 2016年第12期846-848,共3页 Chinese Journal of Rheumatology
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