摘要
目的对冠心病房颤血小板活化功能进行调查研究,为临床应用提供理论依据。方法采用调查问卷的方法对患者进行调查,内容包括患者一般资料、冠心病房颤类型等等,患者填完后收回调查问卷进行分析;对患者血小板的活化因子,如血小板溶酶体膜糖蛋白GP53、α-颗粒膜蛋白P选择素和凝血酶敏感蛋白等的表达水平进行调查研究及统计。结果根据心电图分型,试验组患者中粗波型房颤34例,细波型房颤29例,扑动性房颤20例,慢率型房颤27例,快速型房颤39例,极速型房颤17例;冠心病并发房颤患者血小板溶酶体膜糖蛋白GP53、α-颗粒膜蛋白P选择素和凝血酶敏感蛋白等的表达水平均比单纯冠心病患者高。结论该研究结果对冠心病房颤患者的治疗及冠心病房颤的预防具有重要的临床意义。
Objective To investigate the mobilizing function of atrial fibrillation platelet of coronary disease and provide theoretical basis for the clinical application. Methods The general data and atrial fibrillation type of coronary disease of patients were surveyed by the questionnaires and analyzed after sorting out, and the expression level of activation factors of platelets such as membrane of lysosome glycoprotein GP53, gmp-140 p-selectin and thrombospondin was investigated and counted. Results The electrocardiography somatotype showed that coarse wave atrial fibrillation occurred to 34 cases, fine wave type of atrial fibrillation occurred to 29 cases, flutter atrial fibrillation occurred to 20 cases, slow rate atrial fibrillation occurred to 27 cases, fast rate atrial fibrillation occurred to 39 cases, extreme rate atrial fibrillation occurred to 17 cases,and the expression level of platelets membrane of lysosome glycoprotein GP53, gmp-140 p-selectin and thrombospondin was higher than that of patients with simple coronary disease. Conclusion The research result is of important clinical significance to the treatment and prevention of patients with atrial fibrillation of coronary disease, which is worth promotion.
出处
《中国卫生产业》
2016年第34期178-180,共3页
China Health Industry
关键词
冠心病
房颤
血小板活化功能
调查研究
Coronary disease
Atrial fibrillation
Mobilizing function of platelets
Investigation
