期刊文献+

早期胃癌临床病理特征分析 被引量:2

暂未订购
导出
摘要 目的:探讨早期胃癌临床病理特征。方法:2012年1月至2015年3月选择我院收治的早期胃癌患者30例为研究对象,所有患者都进行了免疫组化病理,同时进行临床特征的记录与分析。结果:在30例患者中,Her2阳性表达24例,阳性表达率为80.0%。同时HER2阳性表达与胃癌的病理类型无关,与TNM分期与淋巴结转移有明显相关性(P<0.05)。结论:早期胃癌患者免疫病理组化显示Her2阳性表达比较高,且与TNM分期与淋巴结转移存在相关性,为此需要加强病理特征分析。
出处 《内蒙古中医药》 2016年第10期101-102,共2页 Inner Mongolia Journal of Traditional Chinese Medicine
  • 相关文献

参考文献4

二级参考文献27

  • 1Jiann-Sheng Su,Yu-Tso Chen,Ren-Ching Wang,Chun-Ying Wu,Shou-Wu Lee,Teng-Yu Lee.Clinicopathological characteristics in the differential diagnosis of hepatoid adenocarcinoma:A literature review[J].World Journal of Gastroenterology,2013,19(3):321-327. 被引量:84
  • 2Stern DF,Heffernan PA,Weinberg RA. p185,a product of the neu proto-oncogene ,is a receptorlike protein associated with tyrosine kinase activity[J]. Mol Cell BioI, 1986,6 (5): 1729-1740.
  • 3Hofmann M, Stoss 0, Shi D, et al. Assessment of a HER2 scoring system for gastric cancer-results[rom a validation study[J]. Histopathology, 2008,52(7): 797-805.
  • 4Wickremesekera A, Hovens CM, Kaye A H . Expression of ErbB-I and 2 in ves tibular schwannomas[l]. J Clin Neurosci ,2007 ,14(12): 1199-1206.
  • 5Fuller SJ,Sivarajah K,Sugden PH. ErbB receptors,t.heir ligands, and the consequences of their activation and inhibition in the myocardium[J]. J Mol Cell Cardiol, 2008,44 (5): 831-54.
  • 6Lee KE, Lee HJ, Kim YH, et al. Prognostic significance of p53, nm23 ,PCNA and c-erbB-2 in gastric cancer[l]. Ipn J Clin Oncol, 2003,33(4): 173-179.
  • 7Park Dr, Yun JW, Park JH, et al. Her-2/neu amplification is an independent prognostic factor in gastric cancer[J]. Dig Dis Sci,2006,51(8): 1371-1379.
  • 8Crabsch H ,Sivakumar S,Gray S,et al. Her-2 expression in gastric cancer: Rare, heterogeneous and of no prognostic value-conclusions from 924 cases of two independent series[J]. Cell Oncol, 2010,32(1-2): 57-65.
  • 9Park DI,Yun JW,Park JH,et al. Her-2/neu amplification is an independent prognostic factor in gastric cancer[J]. Dig Dis Sci ,2006,51(8): 1371-1379.
  • 10Bang Y, Chung H, Sawaki A, et a1. HER2-positivity rates in advanced gastric cancer (GC): results from a large international phase III trial[J]. Clin Oncol,2008,26(15 Suppi) :4526.

共引文献22

同被引文献14

引证文献2

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部