摘要
目的:观察双歧杆菌乳杆菌三联活菌片治疗腹泻型肠易激综合征(IBS-D)肠道菌群失调的临床效果。方法:将120例IBS-D患者随机分为观察组和对照组各60例,对照组予马来酸曲美布汀胶囊。观察组在对照组基础上口服双歧杆菌乳杆菌三联活菌片。两组疗程均6周。比较两组需氧菌(肠球菌、肠杆菌、酵母菌)和厌氧菌(乳杆菌、双歧杆菌、拟杆菌、消化球菌)变化和治疗效果。结果:观察组治疗后厌氧菌明显升高,且显著高于对照组(P<0.01);观察组治疗后需氧菌明显降低,且显著低于对照组(P<0.01);对照组患者的厌氧菌和需氧菌无明显变化;观察组总有效率为95%,显著高于对照组的80%(P<0.05)。结论:双歧杆菌乳杆菌三联活菌片治疗IBS-D肠道菌群失调疗效明显。
Objective To obseve the influence of Bifidobacterium lactobacillus sanlian living bacterium in treating alterationof intestinal flora. Method One hundred tenty IBS-D patiens were randomly divided into control group and observation.Cases of control group（60） were orally taken trimebutinemaleate（tid and 2 granules/time）.Based on control group,observation group was given with added Bifidobacterium lactobacillus sanlian living bacterium（4 tablets/time and bid）.Course of treatment were 6 weeks for both groups.Aerobic bacteria and anaerobic bacteria were compared between two groups after treatment.Efficacy in both groups was statistic analysis. Results After treatment,anaerobic bacteria in observation group was remarkably increased,and was obviously higher than control group（P 〈0.01）.After treatmnt,aerobic bacteria in observation group was obviously decreased,and was lower than control group（P〈 0.01）.Anaerobic bacteria and aerobic bacteria in control group was not changed before and after treatment.Total efficacy of observation group was 95 %,which was remarkably higher than control group 80 with statistical difference（P 〈0.05）. Conclusion Efficacy of Bifidobacterium lactobacillus sanlian living bacterium in treating alteration of intestinal flora is significant.
出处
《深圳中西医结合杂志》
2016年第19期17-19,共3页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
关键词
腹泻型肠易激综合征
双歧杆菌乳杆菌三联活菌片
肠道菌群失调
Irritable bowel syndrome with diarrhea
Bifidobacterium lactobacillus sanlian living bacterium
Intestinal flora
