摘要
目的探讨不同介入治疗时期对急性心肌梗死患者心率震荡的影响。方法选择急性心肌梗死（AMI）患者108例,根据发病至介入治疗开通梗塞相关血管时间分为A组（6小时内）30例、B组（6-12小时）26例、C组（7-10天内）28例,并以同期未行再灌注治疗的急性心肌梗死患者24例为对照组,利用24h动态心电图分析系统获得其室性早搏,分别计算梗死后1周内及治疗后30天各组的震荡初始（TO）和震荡斜率（TS）2个指标。结果梗死后一周内TO值C组（0.74±0.58%）〉B组（0.52±0.38%）〉A组（0.41±0.39%）,P〈0.01,C组与对照组（0.76±0.56%）比较无差别;TS值C组（6.26±2.64ms/RR）
Objective To investigate the impact of intervention period on heart rate shocks in patients with acute myocardial infarction. Methods Chose 108 patients with acute myocardial infarction（ AMI）,according to the interventional treatment of disease to the time of opening of infarct- related artery they were divided into group A（ 6 hours） 30 cases,B group（ 6-12 hours） 26 cases,C group（ 7-10 days） 28 cases,and in the same period 24 patients who did not reperfusion of acute myocardial infarction treated were selected as the control group. Used the 24 h Holter analysis system to obtain its premature ventricular contractions,respectively calculated turbulence onset（ TO） and turbulence slope（ TS） at the time point 1 week after infarction and 30 days after treatment. Results Within one week after infarction TO values in group C（ 0.74 ± 0.58%） B group（ 0.52±0.38%） A group（ 0. 41 ± 0. 39%）,P〈0. 01. There was no significant difference between C group and control group（ 0.76±0.56%）.TS values in group C（ 6.26±2.64 ms / RR） B group（ 10.42±2.48 ms / RR） A group（ 12.54 ± 2. 75 ms / RR）,P〈0. 01. The difference between C group and control group（ 5. 78 ± 2. 53 ms / RR） was not statistically significant. Compared with those before treatment, TO values of the 4 treatment groups were significantly decreased,TS values were significantly increased（ all P〈0. 01）. Analysis of covariance indicated that net treatment effect of TO and TS,△TO and △TS in C group were significantly higher than group A,group B and control group. Difference of △TS and △TO between group A and B had no difference.Conclusions Emergency percutaneous coronary intervention can be immediately improve heart rate turbulence phenomena significantly in patients with AMI,delayed PCI did not significantly improve AMI early heart rate turbulence,but heart rate turbulence phenomena still significantly improved 1 month after infarction,suggesting that early open infarct-related artery,vagus nerve damage reduce and its protective effect increased,the risk of sudden death reduced correspondingly.
出处
《齐齐哈尔医学院学报》
2016年第25期3127-3129,共3页
Journal of Qiqihar Medical University
关键词
急性心肌梗死
心率震荡
急诊介入治疗
Acute myocardial infarction
Heart rate turbulence emergency percutaneous coronary intervention
