期刊文献+

球囊膨肺在气管切开患者肺部并发症防治中的应用 被引量:10

暂未订购
导出
摘要 目的:探讨球囊膨肺在因神经源性疾病致气管切开患者肺部并发症防治中的作用。方法选取2015年1~12月本院重症医学科收治的气管切开患者,将患者随机分为常规治疗组(对照组)和球囊膨肺组(试验组),对照组进行常规气道管理,试验组在常规气道管理基础上进行球囊膨肺。观察两组患者肺CT、呼吸浅快指数、肺顺应性、痰量、肺损伤评分(lung injury score, LIS)、呼吸机接概率。结果共84例因大面积脑出血、脑梗死和颅脑外伤等非肺源性原因致气管切开带管患者入选试验,因各种原因退出9例,最终完成本研究共75例,其中对照组39例,试验组36例;两组基线资料差异无显著性(P值均>0.05)。试验组经球囊膨肺后氧合指数[(285.58±63.25)mmHg(1mmHg=0.133kPa)]高于对照组[(191.85±41.85)mmHg](P<0.01)、呼吸浅快指数[(24.1±6.9)次/L]低于对照组[(37.4±7.5)次/L](P<0.01)、肺顺应性[(188.6±39.1)ml/cmH2O]高于对照组[(131.6±29.7)ml/cmH2O](P<0.01)、24小时痰量[(15.4±5.6)ml]低于对照组[(22.7±9.7)ml](P<0.01)、肺并发症发生率(25.00%)低于对照组(92.31%,P<0.01);心率、呼吸、平均动脉压、LIS均无显著性变化(P值均>0.05)。所有患者无气胸发生。结论球囊膨肺能够改善神经重症气管切开患者的肺部并发症,且无严重并发症发生。
出处 《中国医刊》 CAS 2016年第10期101-104,共4页 Chinese Journal of Medicine
  • 相关文献

参考文献20

  • 1Esteban A, Anzueto A, Frutos F,et al. Characteristics andoutcomes in adult patients receiving mechanical ventilation: a28-day international study [J]. Journal of the American MedicalAssociation, 2002, 287(30):345-355.
  • 2Woratyla SP, Morgan AS, Mackay L, et al. Factors associated withearly onset pneumonia in the severely brain-injured patient [J]、Connecticut Medicine, 1995, 59(11):643-647.
  • 3Pelosi P, Ferguson ND, Frutos-Vivar F, et al. Management andoutcome of mechanically ventilated neurologic patients [J]. CriticalCare Medicine, 2011, 39(6):1482-1492.
  • 4Seder DB, Lee K, Rahman C, et al. Safety and feasibility ofpercutaneous tracheostomy performed by neurointensivists [J].Neurocritical Care, 2009, 10(3):264-268.
  • 5Terragni PP, Antonelli M, Fumagalli R,et al. Early vs latetracheotomy for prevention of pneumonia in mechanically ventilatedadult ICU patients: a randomized controlled trial [J].Journal of theAmerican Medical Association, 2010,303(15):1483-1489.
  • 6Treggiari MM. Hemodynamic management of subarach-noidhemorrhage [J]. Neurocritical Care, 2011, 15(2):329-335.
  • 7Brambrink AM, Dick WF. Neurogenic pulmonary edema.Pathogenesis, clinical picture and therapy[J]. Anaesthesist, 1997,46(11):953-963.
  • 8Holland MC, Mackersie RC, Morabito D, et al. The developmentof acute lung injury is associated with worse neurologic outcome inpatients with severe traumatic brain injury [J]. Journal of Trauma.2003, 55(1):106-111.
  • 9Paulus F, Binnekade JM, Vermeulen M, et al. Manualhyperinflation is associated with a low rate of adverse events whenperformed by experienced and trained nurses in stable critically illpatients: a prospective observational study [J]. Minerva Anestesiol,2010,76(12):1036-1042.
  • 10Patman S, Jenkins S, Stiller K. Physiotherapy does not prevent, orhasten recovery from, ventilator-associated pneumonia in patientswith acquired brain injury Nunn [J]. Intensive Care Med, 2009,35(3):258-265.

二级参考文献13

  • 1ARDS Definition Task Force,Ranieri VM,Rubenfeld GD,et al.Acute respiratory distress syndrome:the Berlin Definition[J].JAMA,2012,307:2526-2533.
  • 2Abroug F,Ouanes-Besbes L,Elatrous S,et al.The effect of prone positioning in acute respiratory distress syndrome or acute lung injury:a meta-analysis.Areas of uncertainty and recommendations for research[J].Intensive Care Med,2008,34:1002-1011.
  • 3Gattinoni L,Tognoni G,Pesenti A,et al.Effect of prone positioning on the survival of patients with acute respiratory failure[J].N Engl J Med,2001,345:568-573.
  • 4Guerin C,Gaillard S,Lemasson S,et al.Effects of systematic prone positioning in hypoxemic acute respiratory failure:a randomized controlled trial[J].JAMA,2004,292:2379-2387.
  • 5Mancebo J,Fernández R,Blanch L,et al.A multicenter trial of orolonged orone ventilation in severe acute respiratory distress syndrome[J].Am J Respir Crit Care Med,2006,173:1233-1239.
  • 6Taccone P,Pesenti A,Latini R,et al.Prone positioning in patients with moderate and severe acute respiratory distress syndrome:a randomized controlled trial[J].JAMA,2009,302:1977-1984.
  • 7Brower RG,Lanken PN,Maclntyre N,et al.National Heart,Lung,and Blood Institute ARDS Clinical Trials Network.Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome[J].N Engl J Med,2004,351:327-336.
  • 8Suh GY,Kwon O J,Yoon JW,et al.A practical protocol for titrating " optimal " PEEP in acute lung injury:recruitment maneuver and PEEP decrement[J].J Korean Med Sci,2003,18:349-354.
  • 9Gattinoni L,Carlesso E,Taccone P,et al.Prone positioning improves survival in severe ARDS:a pathophysiologic review and individual patient meta-analysis[J].Minerva Anestesiol,2010,76:448-454.
  • 10Sud S,Friedrich JO,Taccone P,et al.Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia:systematic review and meta-analysis[J].Intensive Care Med,2010,36:585-599.

共引文献62

同被引文献80

引证文献10

二级引证文献51

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部