摘要
目的探讨阴道彩超与宫腔镜在围绝经期及绝经后期子宫出血中诊治的临床应用价值。方法回顾性分析2014年1月至2015年12月间收治的围绝经期及绝经后期子宫出血患者232例。所有患者完成阴道彩超检查和宫腔镜检查并取活检,并将检查结果与病理学诊断对照对比分析。结果宫腔镜对各个疾病诊断的阳性预测率和真阳性率（敏感度）均较阴道彩超高。其中宫腔镜对宫内膜增生、子宫内膜癌、子宫内膜炎诊断的阳性预测率、敏感度与阴道彩超比较,差异均有统计学意义（P〈0.05）。宫腔镜对子宫内膜息肉诊断的敏感度为87.8%,高于阴道彩超的60.6%,差异有统计学意义（P〈0.05）。宫腔镜对子宫内膜生理性改变的诊断中阳性预测率高于阴道彩超,差异有统计学意义（P〈0.05）。阴道彩超显示,厚度为≥4~10mm组的子宫内膜癌检出率低于厚度〉10mm组,差异有统计学意义（χ^2=6.523,P=0.011）。子宫内膜厚度〈4mm组子宫内膜生理性改变的检出率高于厚度≥4~10mm和厚度〉10mm组,差异有统计学意义（χ^2=6.116,P=0.013和χ^2=22.428,P=0.001）。子宫内膜生理性改变≤10mm组中的检出率高于厚度〉10mm组,差异有统计学意义（χ^2=9.13,P=0.003）。结论围绝经期及绝经后期子宫出血可采用阴道彩超常规筛查,宫腔镜较阴道彩超在明确诊断上更有优势,值得临床推广。
Objective To investigate the clinical value of transvaginal color Doppler ultrasonography and hysteroscopy in perimenopausal and postmenopausal patients with uterine bleeding.Methods A total of 232 cases of patients with uterine bleeding from January 2014 to December 2015 were selected and analyzed retrospectively in the hospital.All patients underwent transvaginal color Doppler ultrasound examination and hysteroscopy and biopsy,and the results were compared with pathological diagnosis results.Results The positive predictive rate and true positive rate（sensitivity）of hysteroscopy in all diseases were higher than those of the transvaginal color Doppler ultrasonography.The positive predictive rates and true positive rates of endometrial hyperplasia,uterine endometrial carcinoma and endometritis detected by hysteroscopy were all significantly higher than that detected by transvaginal color Doppler ultrasound（P〈0.05）.The sensitivity of hysteroscopy in the diagnosis of endometrial polyps（87.8%）was significantly higher than that of transvaginal color Doppler ultrasound（P〈0.05）.The positive predictive rate of hysteroscopy in the diagnosis of endometrial physiological changes was significantly higher than that of the transvaginal color Doppler ultrasound（P〈0.05）.The detective rate of endometrial carcinoma in the group of endometrial thickness from 4to 10 mm was significantly lower than that of the thickness higher than 10mm（χ^2=6.523,P=0.011）.And the detective rate of physiological changes in the group of endometrial thickness lower than 4mm was significantly higher that of the thickness from 4to 10 mm group（χ^2=6.116,P=0.013）and the thickness higher than 10 mm group（χ^2=22.428,P=0.001）.In addition,the detective rate of physiological changes in the group of endometrial thickness lower than 10 mm was significantly higher than that of thickness higher than 10mm（χ^2=9.13,P=0.003）.Conclusion Transvaginal color Doppler ultrasound could be used in screening the perimenopausal and postmenopausal patients with uterine.And hysteroscopy has more advantages in the diagnosis of gynecological disease compared with transvaginal color Doppler ultrasound,which is worthy of clinical value.
出处
《检验医学与临床》
CAS
2016年第21期3026-3028,3031,共4页
Laboratory Medicine and Clinic
关键词
阴道彩超
宫腔镜
围绝经期
绝经后期
子宫出血
子宫内膜厚度
transvaginal color Doppler ultrasonography
hysteroscopy
perimenopausal
postmenopausal
uterine bleeding
endometrial thickness
