摘要
目的:探讨肺癌患者中医体质及中医辨证分型与临床TNM分期及病理类型之间的关系,旨在为肺癌的中医药个体化治疗提供客观的理论依据。方法:收集本院门诊及住院部120例明确诊断、病理类型及临床分期的肺癌患者作为研究对象,采用标准化的9种中医体质分类量表对其进行肺癌中医体质问卷调查,调查研究所需资料,并录入Execl表,建立数据库。结果:肺癌患者不同临床TNM分期与中医体质具有显著的相关性(P<0.05);其中TNMⅠ期、Ⅱ期痰湿质为主,其次为湿热质,TNMⅢ期、Ⅳ期以阴虚质为主,其次为阳虚质、气虚质及气郁质。肺癌患者不同临床TNM分期与中医辨证分型有显著的相关性(P<0.05);其中TNMⅠ期以气虚痰湿证为主,占66.7%;Ⅱ期以气虚痰湿证为主,占50%;Ⅲ期以气阴两虚证为主,占37.3%;Ⅳ期以气阴两虚证为主,占53.4%。肺癌中医体质与病理类型之间无明显相关性(P>0.05)。结论:肺癌患者中医体质与临床TNM分期有一定相关性,与病理类型无明显相关性;肺癌中医辨证分型与临床TNM分期具有相关性。
Objective： To study the relationship between lung cancer clinical TNM staging,pathological patterns and constitution types,differentiation of syndromes in Chinese medicine,which was designed to provide the objective clinical basis for the individualized treatment of lung cancer with Chinese medicine. Methods： 120 cases that were diagnosed lung cancer were collected to be taken as the research objects. The questionnaire survey form was used,input the data into the Excel,and set up a database. Results： The correlation between different clinical TNM staging in lung cancer patients and constitution types of Chinese medicine had statistical significance（ P〈0. 05）; phlegm- dampness constituion in TNM I and II stages was the common- seen,dampness-heat was the second,deficiency of yin in the TNM III and IV stages was the common- seen,then was yang deficiency,qi deficiency and qi stagnation constitutions. The correlation between different clinical TNM staging in lung cancer patients and differentiation of syndromes in Chinese medicine had statistical significance（ P〈0. 05）,in TNM I stage,the most common- seen syndrome was qi deficiency and phlegm dampness,which was 66. 7%（ 2 /3）,in II stage,qi deficiency and phlegm dampness syndrome was also common- seen,which was 50%（ 4 /8）,in III stage,the most common- seen syndrome was deficiency of both qi and yin,which was 37. 3%（ 19 /51）,in Ⅳ stage,it was the same as III stage,which was 53. 4%（ 31 /58）. There was no significant difference between constitutional types of patients and pathological patterns. Conclusion： Constitution types of patients with lung cancer are related to TNM stages,not related to pathological patterns; syndromes differentiation has been involved in lung cancer clinical TNM staging.
出处
《中国中医药科技》
CAS
2016年第5期506-509,共4页
Chinese Journal of Traditional Medical Science and Technology
基金
浙江省宁波市科学计划项目(2013A29)
浙江省慈溪市民生类科技计划项目(CN2012031)
关键词
肺肿瘤
体质学说
辨证分型
@TNM分期
肿瘤
组织学类型
人类
lung cancer
constitution theory
differentiation of syndromes
TNM staging
cancer
histological type
human being
