卢立康唑乳膏治疗体股癣疗效观察被引量：1

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摘要目的观察和评价卢立康唑乳膏治疗体、股癣的疗效和安全性。方法 80例患者随机分为治疗组﹙卢立康唑乳膏﹚和对照组﹙盐酸阿莫罗芬乳膏﹚治疗,两组均1次/d,共治疗2周。用药后及停药2周评价临床和真菌学疗效。结果治疗组、对照组在停药两周时真菌清除率分别为100.00﹪、87.50﹪﹙χ2=3.41 P﹥0.05﹚,临床疗效用药后2周时,两组总有效率比较,无统计学差异﹙P>0.05﹚。但在停药2周后治疗组、对照组临床疗效分别为100.00℅、85.00℅,两组有统计学意义﹙χ2=4.50,P<0.05﹚。结论卢立康唑乳膏治疗体、股癣疗效好,安全性高,外用方便,每天只需1次,而且具有明显后续效应,是治疗皮肤真菌病的又一个新的选择。

作者赵志明胡亚莹曹爱华高宇

机构地区江苏省泰州市姜堰区皮肤病防治所

出处《皮肤病与性病》 2016年第5期355-357,共3页 Dermatology and Venereology

关键词卢立康唑乳膏体、股癣疗效安全性

分类号 R751.05 [医药卫生—皮肤病学与性病学] R756.2 [医药卫生—皮肤病学与性病学]

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1符美华,李岷,李若瑜,王爱平,温海,郭在培,郝飞,席丽艳,于浩,佘晓东,陈伟,沈永年,胡素泉,刘维达.不同疗程1％卢立康唑乳膏治疗足癣的多中心、随机双盲对照研究[J].中华皮肤科杂志,2014,47(7):453-456. 被引量：16
2王玲,吕雪莲,刘维达.新型咪唑类抗真菌外用药物卢立康唑[J].国际皮肤性病学杂志,2013,39(5):297-299. 被引量：3

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1Ghannoum MA, Long L, Kim HG, et al. Efficacy of terbinafine compared to lanoconazole and luliconazole in the topical treatment of dermatophytosis in a guinea pig model. Med Mycol, 2010, 48(3): 491-497.
2Ghannoum MA, Welshenbaugh A, lmamura Y, et al. Comparison of the in vitro activity of terbinafine and lanoconazole against dermatophytes. Mycoses, 2010, 53 (4): 311- 313.
3Kawakami Y, Oyama N, Sakai E, et al. Childhood tinea incognito caused by Ttichophyton mentagrophytes var. interdigitale mimicking pustular psoriasis. Pediatr Dermatol, 2011, 28 (6): 738-739.
4Saito R, Sawada M, Ishizaki S, et al. A case of inflammatory tinea corporis by Epidermophyton tloccosum. Nihon lshinkin Gakkai Zasshi, 2008, 49 (3): 211-215.
5Jerajani H, Janaki C, Kumar S, et al. Comparative assessment of the efficacy and safety of sertaconazole (2%) cream versus terbinafine cream (1%) versus ulieonazoe (1%) cream in patients with dermatophytoses: a pilot study. Indian J Dermatol, 2013_ 58(1 ): 34-38.
6Katoh T . Guidelines for diagnosis and treatment of mucocutaneous candidiasis. Nihon Ishinkin Gakkai Zasshi, 2009, 50(4): 207-212.
7Uchida K, Nishiyama Y, Tanaka T, et al. In vitro activity of novel imidazole antifungal agent NND-502 against Malassezia species. Int J Antimicrob Agents, 2003, 21 (3): 234-238.
8-Koga H, Nanjoh Y, Makimura K, et al. In vitro antifungal activities of luliconazole, a new topical imidazole. Med Mycol, 2009, 47(6): 640-647.
9Koga H, Tsuji Y, Inoue K, et al. In vitro antifungal activity of lulieonazole against clinical isolates from patients with dermatomycoses. J Infect Chemother, 2006, 12(3): 163-165.
10Oku Y, Takahashi N, Yokoyama K. Fungicidal activity of liranaftate against dermatophytes. Nihon Ishinkin Gakkai Zasshi, 2009, 50( 1 ): 9-13.