摘要
本文报告用静注乙型肝炎免疫球蛋白(HBIG)预防输血后乙型肝炎,结果在90例(保护组50例,对照组40例)受血者中,感染HBV者共11例,前者2例(4％),后者9例(22.5％),两组有非常显著性差异(P<0.01)。误输HBV阳性血者,其HBY感染率分别为7.1％和66.7％,两组亦有非常显著性差异(P<0.01)。静注HBIG对患者的保护率为89.4％。结果证明,静注HBIG对输血后乙型肝炎(HB-PTH)的预防有良好的效果。用于误输HBV阳性血及意外暴露者的立即预防,将是非常有价值的。
Using the intravenous hightitred hepatitis B immunoglobulin (HBIG) to prevent post-transfusion hepatitis B was reported. Of the 90 recipients, 50 cases were in the HBIG group and 40 cases were in the control group. All together 11 cases of HBV infection were found. There were 2 cases (4%) in the HBIG group and 9 cases (22.5%) were in the control group, with the difference between them being very significant (P<0.01).The incidence rate of the cases transfused with HBV positive blood by error in the HBIG group and the control group was 7.1% and the 66.7% respectively, with the difference between them being also signif icant(P<0.01). Therefore, the protective rate reached by administering the IVHBIG to the patients was 89.4%. The results of Study showed that the effect of using the IVHBIG to prevent the post-transfusion hepatitis B was very good. And so it will be very worthy to use the IVHBIG as an immediate prophylaxis of HBV-infection in those transfused with HBV-positive blood by error and those exposed to HBV by chance.
出处
《中国输血杂志》
CAS
CSCD
1991年第4期168-171,共4页
Chinese Journal of Blood Transfusion
