期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

内皮祖细胞在缺血性脑血管病中的研究进展 被引量：1

原文传递
导出
摘要 1背景 脑血管病是全球第二大常见死因，也是成年人最主要的致残原因。随着老龄化社会的发展，脑血管病的发病率逐渐增高。其中，ICVD（Ischemic cerebrovascular disease）占脑血管病的87％跚。目前，药物溶栓和血管内介入治疗是公认的治疗ICVD的有效方法眦。但溶栓治疗时间窗短暂，仅为3～4．5h，因此只有约5％的ICVD患者成功接受溶栓治疗。血管内介入治疗后2年内脑卒中再发率明显高于药物溶栓。
作者 王琪 王满侠 郑婷 张帅杰 张新燕
机构地区 兰州大学第二医院神经内科
出处 《卒中与神经疾病》 2016年第4期298-301,共4页 Stroke and Nervous Diseases
基金 甘肃省卫生行业科研计划项目(编号为GSWSKY-2015-56)
关键词 缺血性脑血管病 内皮祖细胞 血管内介入治疗 药物溶栓 ICVD 老龄化社会 治疗时间窗 介入治疗后
分类号 R743.31 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献46

  • 1Moskowitz MA, Lo EH, Iadecola C. The science of stroke:mechanisms in search of treatments[J]. Neuron,2010,67(2):181-198.
  • 2Sun F,Wang X,Mao X,et al. Ablation of neurogenesis attenu-ates recovery of motor function after focal cerebral ischemia inmiddle-aged mice[J]. PLoS One,2012,7(10) :e46326.
  • 3Shiber JR,Fontane E,Adewale A. Stroke registry: hemorrhag-ic vs ischemic strokes[J]. Am J Emerg Med,2010,28(3) :331-333.
  • 4Molina CA. Reperfusion therapies for acute ischemic stroke ;current pharmacological and mechanical approaches [ J ].Stroke,2011,42(1 Suppl) :S16-S19.
  • 5Shobha N,Buchan AM,Hill MD. Thrombolysis at 3-4. 5 hoursafter acute ischemic stroke onset - evidence from the Canadianalteplase for stroke effectiveness study (CASES) registry[J].Cerebrovascular Diseases?2011,31(3) :223-228.
  • 6Adeoye O,Homung R,Khatri P, et al. Recombinant tissue-type plasminogen activator use for ischemic stroke in the Unit-ed States: a doubling of treatment rates over the course of 5years[j]. Stroke,2011,42(7) : 1952-1955.
  • 7Lutsep HL, Lynn MJ, Cotsonis GA,et al. Does the stentingversus aggressive medical therapy trial support stenting forsubgroups with intracranial stenosis? [J]. Stroke, 2015, 46(11):3282-3284.
  • 8Bogoslovsky T, Chaudhry A, La tour L, et al. Endothelial pro-genitor cells correlate with lesion volume and growth in acutestroke[J]. Neurology, 2010,75 (23) : 2059-2062.
  • 9Isner JM, Kalka C,Kawamoto A,et al. Bone marrow as asource of endothelial cells for natural and iatrogenic vascularrepair[J]. Ann N Y Acad Sci,2001,953:75-84.
  • 10Hur J, Yoon CH?Kim HS,et al. Characterization of two typesof endothelial progenitor cells and their different contributionsto neovasculogenesis[J]. Arterioscler Thromb Vase Biol?2004,24(2):288-293.

二级参考文献15

  • 1Vose J M, Ho A D, Coiffier B, et al. Advances in mobilization for the optimization of autologous stem cell transplantation[J]. Leuk Lymphoma, 2009, 50(9): 1412-1421.
  • 2Blum A, Childs R W, Smith A, eta/. Targeted antagonism of CXCR4 mobilizes progenitor ceils under investigation for cardiovascular disease [ J]. Cytotherapy, 2009, 11 (8) : 1016 - 1019.
  • 3Paczkowska E, Dabkowska E, Nowacki P, et al. Stem cell-based therapy in central nervous system diseases [ J ]. Neurol Neurochir Pol, 2009, 43(6) : 550 -558.
  • 4Stumm R K, Rummel J, Junker V, et al. A dual role for the SDF-1/ CXCR4 chemokine receptor system in adult brain: isoform-selective regulation of SDF-1 expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia[ J]. J Neurosci, 2002, 22(14): 5865-5878.
  • 5Shyu W C, Lin S Z, Yang H I, et al. Functional recovery of stroke rats induced by granulocyte colony-stimulating factor-stimulated stem ceils [J]. Circulation, 2004, 110(13) : 1847 - 1854.
  • 6Shi Q, Hodara V, Butler S D, et al. Differential bone marrow stem cell mobilization by G-CSF injection or arterial ligation in baboons[ J]. J Cell Mol Med, 2009, 13(8B) : 1896 - 1906.
  • 7Ward N L, Lamanna J C. The neurovascular unit and its growth factors: coordinated response in the vascular and nervous systems [J]. Neurol Res, 2004, 26(8) : 870 -883.
  • 8Thored P, Wood J, Arvidsson A, et al. Long-term neuroblast migration along blood vessels in an area with transient angiogenesis and increased vascularization after stroke [ J ]. Stroke, 2007, 38 ( 11 ) : 3032 - 3039.
  • 9Longa E Z, Weinstein P R, Carlson S, et al. Reversible middle cerebral artery occlusion without craniectomy in rats[J]. Stroke, 1989, 20(1) : 84 -91.
  • 10Verfaillie C M, Schwartz R, Reyes M, et al. Unexpected potential of adult stem cells[J]. Ann NY Acad Sci, 2003, 996:231 -234.

共引文献5

同被引文献14

引证文献1

卒中与神经疾病
2016年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部