摘要
目的探讨超声乳化术对青光眼眼内压及角膜内皮细胞的影响。方法2011年8月~2015年2月选择在笔者医院诊治的青光眼患者92例(92只眼),根据人院顺序分为对照组与治疗组各46例,对照组给予玻璃体切割手术,治疗组给予超声乳化术,观察两组术后眼内压、角膜水肿程度和角膜内皮细胞变化情况。结果两组术后1个月的眼内压分别为12.98±4.33和16.24±3.49mmHg,都明显低于术后1天的23.45±7.21和23.10±6.35mmHg,同时治疗组术后1个月的眼内压明显低于对照组(P〈0.05)。治疗组术后1个月的角膜水肿程度明显轻于对照组,差异有统计学意义(P〈0.05)。两组术后1个月的细胞密度与细胞面积变异系数都低于术后1天(P〈0.05),同时治疗组术后1个月的细胞密度与细胞面积变异系数明显少于对照组(P〈0.05)。结论超声乳化术在青光眼患者中的应用能促进眼内压的降低,减轻对于角膜内皮细胞的损伤,减少术后角膜水肿程度,应用安全性佳,值得推广应用。
Objective To investigate the intraoeular pressure and corneal endothelium effects of phacoemulsification in the treatment of the glaucoma patients.Methods From August 2011 to February 2015 in our hospital,92 patients(92 eyes)with glaucoma were selected in our hospital and were accorded to the order of admission were equally divided into control group and treatment group of 46 patients,the control group were received vitrectomy surgery,the treatment group were given the phacoemulsification,observed the postopera-tive intraocular pressure,corneal edema and corneal endothelial cell changes.Results The postoperative lmonth intraocular pressurein the two groups were 12.98±4.33 and 16.24±3.49mmHg respectively that were significantly lower than postoperative 1 day of 23.45±7.21 and 23.10±6.35mmHg,while the treatment group were significantly lower than the control group(P〈0.05).The postoperative lmonth extent of corneal edema in the treatment group were significantly lighter than the control group that compared were statistically sig-nificant difference(P〈0.05).The postoperative lmonth cell density and coefficient of variation of cell area in the two groups were less than postoperative 1 day(P〈0.05),while the postoperative lmonth cell density and coefficient of variation of cell area in treatment group were also significantly less than the control group(P〈0.05).Conclusion Application of phacoemulsification in patients with glaucoma can promote lower intraocular pressure,reduce the corneal endothelial cell damage and postoperative corneal edema,its application security is good that should be widely applied.
作者
陈景成
孙鹏
张洪洋
Chen Jingcheng;Sun Peng;Zhang Hongyang(Facial Features Section,The Fifth People's Hospital of Longgang District,Guangdong 518000,China)
出处
《医学研究杂志》
2016年第9期95-97,101,共4页
Journal of Medical Research
基金
广东省医学科研基金资助项目(A2014043)
关键词
超声乳化术
青光眼
眼内压
角膜内皮细胞
Phacoemulsification
Glaucoma
Intraocular pressure
Corneal endothelium
