摘要
目的：分析医院阿片类镇痛药临床用药的相关因素，为合理用药提供参考。方法：统计2013年阿片类镇痛药品用药处方，并对药物利用指数（DUI）进行有效评价。结果：研究结果显示盐酸吗啡片、芬太尼注射液的DUI小于l，而盐酸吗啡注射液、硫酸吗啡缓释片、盐酸哌替啶注射液、磷酸可待因片、盐酸羟考酮控释片和阿桔片的DUI大于l。结论：对于晚期癌症患者的镇痛治疗，应首选盐酸羟考酮控释片或硫酸吗啡缓释片，而口服阿片类镇痛药物的DUI在1～2之间，这种临床选药较为合理。
Objective： To analyze the related factors of clinical medication on opioids analgesics in a hospital and to provide the reference for rational drug use. Methods： 2013 opioids analgesic drug prescriptions were statistically ana- lyzed. And the drug utilization index （DUI） were evaluated. Results： Studies shown that morphine hydrochloride tablet and fentanyl injection of less than 1 DUI, however, the DUI of morphine hydrochloride injection, morphine sulfate sustained release tablets, pethidine hydrochloride injection, codeine phosphate tablets, oxycodone hydrochloride retard-20 tablet, opioid and platycodon grandiflorum is greater than 1. Conclusion： For patients with advanced cancer pain treat- ment, the drug of choice is oxycodone hydrochloride controlled-release tablets, morphine sulfate sustained-release tablets, oral opioid analgesics, requiring drug utilization index between 1 and 2 （DUI）, which the clinical application of the more reasonable, analgesia clinical application of analgesic drugs to be reasonable.
出处
《抗感染药学》
2016年第4期769-771,共3页
Anti-infection Pharmacy
