摘要
目的探讨中老年社区居民糖化血红蛋白（hemoglobin Alc，HbAlc）水平与代谢综合征（metabolic syndrome，MS）及各种代谢紊乱的相关性。方法2011年7月，对郑州市四个社区8237名社区居民进行问卷调查、体格检查和实验室检查，按照HbA1c〈5．7％，5．7％～，6．5％一分组后调查MS及各种代谢紊乱的患病率，采用Pearson相关分析探讨HbAlc与MS及各项代谢指标的相关性。结果中老年社区居民HbA1c水平较高，MS和各种代谢紊乱随着HbA1c水平的升高而升高，当HbA1c≥6．5％时，MS、中心性肥胖、高甘油三酯（high triglyceride，H—TG）血症、低高密度脂蛋白胆固醇（highdensity lipoprotein cholesterol，HDL—C）血症的患病率分别为81．7％、78％、50．8％、58％。HbA1c与HDL—C呈负相关；与腰围、体重指数、舒张压、胆固醇、甘油三酯、低密度脂蛋白胆固醇、糖耐量试验2h血糖呈正相关。结论2011年郑州市社区中老年人群HbA1c水平较高，HbA1c≥6．5％时MS和各种代谢紊乱的患病率较高，HbA1c与MS和各种代谢紊乱有较强相关性。
Objective To investigate hemoglobin Alc {HbAlc） level in the middle - aged and elderly community residents and its correlations with metabolic syndrome （MS} and other metabolic disorders. Methods Questionnaire survey, physical examination and laboratory examination were conducted in 8,237 middle - aged and elderly residents in 4 communities in Zhengzhou City in July, 2011. The prevalence of MS and various metabolic disorders were investigated for groupswith HbAlc 〈 5.7%, 5.7% - and 6.5% -. The correlations of HbAlc with MS and various metabolic disorders were explored by Pearson correlation anlysis. Results The HbAlc level of the middle - aged and elderly residents was high. The prevalence of MS and various metabolic disorders rised with HbAle level. When HbAlc was 6.5% or higher, the prevalence of MS, central obesity, high triglyceride I H - TG） and low high density lipoprotein cholesterol （ HDL - C） was 81.7%, 78.0%, 50.8% and 58.0% respectively. HbAlc was negatively correlated with HDL - C, but positively correlated with waist circumference （WC）, body mass index （BMI）, diastolic blood pressure （DBP） , total cholesterol （TC）, TG~ low density lipoprotein cholesterol（ LDL - C ）, 2 - hour plasma glucose in the oral glucose tolerance test （ 2hPG） . Conclusions The HbAlc level of the middle - aged and elderly community residents in Zhengzhou City in 2011 is high. When HbAlc is 6.5% or higher, the prevalence of MS and various metabolic disorders increases, and there are strong correlations between HbAlc and MS and various metabolic disorders.
出处
《实用预防医学》
CAS
2016年第10期1229-1231,共3页
Practical Preventive Medicine
关键词
代谢综合征
代谢异常
糖化血红蛋白
社区居民
Metabolic syndrome
Metabolic disorders
Hemoglobin A1c（ HbAlc）
Community residents
