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慢性阻塞性肺疾病急性加重期患者血清降钙素原及高敏C反应蛋白水平的变化及其临床意义 被引量:2

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摘要 目的探讨慢性阻塞性肺疾病急性加重期患者血清降钙素原及高敏C 反应蛋白水平的变化及其临床意义.方法随机选取 2013 年 4 月至 2016 年 4 月我院收治的 80 例慢性阻塞性肺疾病急性加重期患者,将这些患者作为研究组,另选取80名健康人员作为对照组,对两组人员的血清PCT、hs-CRP 水平、研究组患者的痰病原学检查结果及不同预后患者的血清PCT、hs-CRP 水平进行统计分析.结果研究组患者的血清PCT、hs-CRP 水平均显著高于对照组(P〈0.05),达到了85.0%的细菌感染发生率和22.5%的死亡率,死亡患者的血清PCT、hs-CRP 水平均显著高于存活患者(P〈0.05).结论慢性阻塞性肺疾病急性加重期患者血清降钙素原及高敏C 反应蛋水平均较高,对其进行检测能够对患者病情发生发展及严重程度进行预测. ObjectiveTo study the chronic obstructive pulmonary disease in patients with acute aggravating period of serum calcitonin original and high-sensitivity c-reactive protein level change and its clinical significance.Methodsrandomly selected from April 2013 to April 2016 our hospital 80 cases of chronic obstructive pulmonary disease in patients with acute aggravating period, these patients as a team, the other selected 80 healthy persons as control group, the two groups of serum PCT, hs - CRP level, the team in patients with sputum etiology and prognosis in patients with the results of the tests of serum PCT, hs CRP levels were analyzed.Resultsthe team of the patient's serum PCT, hs CRP levels were significantly higher than that of control group (P 〈 0.05), the bacterial infection incidence of 85.0% and 22.5% of the mortality and death of the patient's serum PCT, hs CRP levels were significantly higher than survival patients (P 〈 0.05).Conclusionchronic obstructive pulmonary disease in patients with acute aggravating period of serum calcitonin original and high-sensitivity c-reactive protein levels are high, can detect the patient condition to predict development and severity.
作者 刘莉 罗晨
出处 《湖南中医药大学学报》 CAS 2016年第A01期42-42,共1页 Journal of Hunan University of Chinese Medicine
关键词 慢性阻塞性肺疾病急性加重期 血清降钙素原 高敏C反应蛋白 变化 临床意义 Acute exacerbation of chronic obstructive pulmonary disease period Serum calcitonin original High-sensitivity c-reactive protein Change Clinical significance
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  • 1管希周,刘又宁,罗燕萍,佘丹阳,周光,陈良安,徐雅萍.同时产DHA-1型头孢菌素酶和SHV-12型超广谱β内酰胺酶的肺炎克雷伯菌[J].中华结核和呼吸杂志,2005,28(7):475-478. 被引量:13
  • 2周承惇,陆泽元,任南征,张贵昌.降钙素原在呼吸机相关性肺炎中的诊断价值[J].中国危重病急救医学,2006,18(6):370-372. 被引量:38
  • 3慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量:8237
  • 4Peduzzi P, Shatney C, Sheagren J, et al. Predictors of bacteria and gram negative bacteria in patients with sepsis. The veterans affairs sys- temic sepsis cooperative study group [ J ]. Arch Intern Med, 1992, 152 (3): 529-535.
  • 5Assicot M, Gendrel D, Carsin H, et al. High serum procalcitonin con- centrations in patients with sepsis and infection [J]. Aneet, 1993, 341 (8844) : 515 -518.
  • 6Nylen ES, Whang KT, Snider RH Jr, et al. Mortality is increased by procaleitonin and decreased by an antiserum reactive to procaleitonin in experimental sepsis [J]. Crit Care Med, 1998, 26:1001 -1006.
  • 7Briel M, Christ - Crain M, Young J, et al. Procalcitonin - guided an- tibiotic use versus a standard approach for acute respiratory tract infec- tions in primary care: study protocol for a randomised controlled trial and baseline. Characteristics of participating general practitioners [ J ]. Arch Intern Med, 2008, 168 (18) : 2000 -2007.
  • 8Christ - Crain M, Jaccard-Stolz D, Bingisser R, et al. Effect of pro- calcitonin- guided treatment on antibiotic use and outcome in lower re- spiratory tract infections : cluster - randomised, single - blinded inter- vention trail [J]. lancet, 2004, 363 (9409) : 600 -607.
  • 9]aye DL, Waites KB. Clinical applications of C - reactive protein in pediatrics [J]. Pediatr Infect Dis J, 1997, 16: 735-747.
  • 10World Health Orgnization. The top 10 causes of death. [ EB/OL]. 2011-07-21. http ://www. who. int/mediacentre/factsheets/fs310/ en/index, html.

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