摘要
目的:探讨临床药师在复杂感染患儿抗感染治疗中的作用。方法:临床药师参与1例因溺水致肺部感染及脑脓肿患儿的治疗过程,协助医师调整抗菌药物治疗方案,并根据病原菌特点、治疗效果及药品不良反应,先后提出抗革兰氏阳性和阴性菌药物调整、万古霉素剂量调整、万古霉素不良反应及其处理、抗侵肺巴斯德菌药物的选择、加强抗真菌感染治疗等建议。结果:医师部分采纳临床药师建议,经过5次抗感染治疗方案的调整,患儿肺部及脑部的感染得到了有效控制,不良反应症状消失。结论:临床药师参与复杂感染患儿的治疗过程,结合患儿病原学检查结果,协助医师制订安全、有效的抗感染方案,及时处理药品不良反应,并积极开展抗菌药物疗效评估及药学监护,对患儿的治疗起到了积极的作用。
OBJECTIVE：To explore the role of clinical pharmacists participating in anti- infective treatment for a child with complex infection. METHODS：Clinical pharmacists participated in treatment process of one child with pulmonary infection and brain abscess after a near-drowning incident,assisted physicians to adjust antibiotics therapy plan,and put several suggestions as the adjustment of anti-gram-positive and anti-gram-negtive bacterium drugs,the dosage adjustment of vancomycin,vancomycin-induced ADR and disposal,the selection of anti-Pasteurella pneumotropica drugs,the enhancement of anti-fungal infection therapy,according to pathogen characteristics,treatment effect and ADR. RESULTS：Physicians partly adopted the advice of clinical pharmacists,the child＇s pulmonary and brain infection were controlled effectively and ADR disappeared after 5 times of adjusting anti-infective the rapy plan. CONCLUSIONS：Clinical pharmacists participate in the treatment process of one child with complex infection,and assist physicians to formulate safe and effective anti-infective plan according to the results of etiological examination;dispose ADR timely and carry out efficacy evaluation of antibiotics and pharmaceutical care,that can give positive effects on patient treatment.
出处
《中国药房》
CAS
北大核心
2016年第26期3725-3728,共4页
China Pharmacy
关键词
临床药师
肺部感染
脑脓肿
溺水
药学监护
Clinical pharmacist
Pulmonary infection
Brain abscess
Near-drowning
Pharmaceutical care
