摘要
目的探讨血液病患者产生血小板抗体的影响因素及血小板抗体阳性患者经血小板交叉配型后的输注效果。方法用全自动血型仪,采用固相抗体检测法进行血小板抗体筛选及交叉配型,对血小板输注有效率进行统计学分析。结果血小板相关抗体的产生与妊娠史、输血史相关,对产生抗体的患者进行血小板交叉配型后,24h CCI>4.5者为86.7%。结论对于血小板抗体阳性的患者,在保证同型输注的基础上进行血小板交叉配型可以极大的提高血小板输注效率,减少血小板输注无效症的发生。
Objective To investigate the influential factors for the appearance of platelet antibody in hematological patients and to analyze the effect of matched platelet by crossmatch. Methods The antibodies in the platelet of patients were screened. The positive ones were selected to perform the platelet crossmatch using a solid-phase antibody detection system in an automatic machine. Results The production of platelet antibodies is related to the history of pregnancy and blood transfusion. After platelet crossmatch,86. 7% of the patients had 24 h CCI 〉 4. 5. Conclusion Crossmatch of platelet can greatly improve the efficiency of platelet transfusion.
出处
《中国输血杂志》
CAS
北大核心
2016年第7期711-712,共2页
Chinese Journal of Blood Transfusion
关键词
血小板抗体
交叉配型
血小板输注无效
临床应用
platelet antibodies
crossmatch
platelet refractoriness
clinical application
