摘要
目的观察对比单纯切除缝合、单纯切除缝合+^(90)Si-^(90)Y放射性核素敷贴治疗和整形外科手术+^(90)Si-^(90)Y放射性核素敷贴治疗瘢痕疙瘩的临床效果。方法瘢痕疙瘩患者183例(210块),根据治疗方法分为:单纯切除缝合(A组)42块,单纯切除缝合+放射性核素敷贴治疗(B组)54块,整形外科手术+放射性核素敷贴治疗(C组)114块。分别比较三种治疗方法的临床疗效。结果所有患者均获得随访,随访时间6~24个月,平均16个月。三组治疗后的总有效率差异有显著性(P<0.05),其中B组、C组治疗有效率均明显高于A组,且C组治疗有效率明显高于B组。A组和B组比较,χ~2=7.54,P<0.05;A组和C组比较χ~2=48.4,P<0.05;B组和C组比较χ~2=9.01,P<0.05。结论联合整形外科手术+^(90)Si-^(90)Y放射性核素敷贴治疗瘢痕疙瘩能有效治疗瘢痕疙瘩,优于单纯切除缝合和单纯切除缝合+^(90)Si-^(90)Y放射性核素敷贴治疗。
Objective In this study,the clinical efficacy of three different methods,including surgery,surgery combined with ^90Si-^90Y isotope stickers and plastic surgery combined with ^90Si-^90Y isotope stickers,was observed in the treatment of keloids.Method Altogether 183 keloid patients（210 keloid scars） were allocated into the following groups：42 keloid scars in the surgery group（A）,54 in the surgery combined with isotope stickers group（B）,and 114 in plastic surgery combined with isotope stickers group（C）.The clinical efficacy of the three treatment methods was compared.Result All patients were followed up for 6-24 months with an average of 16 months.There are significant differences in the clinical efficacy among the three groups（P〈0.05）.The efficacy for the groups B and C was significantly higher than the group A,whereas the efficacy for the group C was much higher than the group B.When the differences between the any two groups were calculated,the value of χ^2 is 7.54 48.4,and 9.01 between groups A and B（P〈0.05） groups A and C（P〈0.05） and groups B and C（P〈0.05）,respectively.Conclusion The clinical efficacy for plastic surgery combined with ^90Si-^90Y isotope stickers was much better than surgery and surgery combined with ^90Si-^90Y isotope stickers in the treatment of keloids.
出处
《中国临床医生杂志》
2016年第9期32-34,共3页
Chinese Journal For Clinicians
