摘要
目的：探讨声带白斑病理特征及内镜下黏膜剥脱术的预后。方法对186例声带白斑患者进行回顾性分析，分析其病理特点及其与内镜下黏膜剥脱术预后的关系。结果186例声带白斑中单纯增生伴角化或不全角化的有87例（46．8％），复发17例，癌变3例；轻度不典型增生的有64例（34．4％），复发15例，癌变7例；中度不典型增生的有29例（15．6％），复发13例，癌变10例；重度不典型增生或原位癌的有6例（3.2％），复发 6例，癌变 5例。结论声带白斑组织病理特征与其复发、癌变相关，病理分级越高，复发、癌变风险越高。
Objective To investigate the pathological features and prognostic analysis in endoscopic strip-ping microflap excision of vocal cords leukoplakia.Methods A total of 186 cases with vocal cord leukoplakia and treated by endoscopic stripping microflap excision were retrospectively analyzed,calculated the ratios of recurrence and malignant transformation on keratosis without dysplasia,mild dysplasia,moderate dysplasia and severe dysplasia and carcinoma in situ.Then,the association of histopathological classification with recurrence and malignant transformation in vocal cord leukoplakia were evaluated.Results 87 cases of all 186 patients with vocal cord leukoplakia were kera-tosis without dysplasia,17 cases were recurrenced and 3 cases were developed to carcinoma;64 cases were mild dysplasia,15 cases were recurrenced and 7 cases were developed to carcinoma;29 cases were moderate dysplasia, 13 cases were recurrenced and 10 cases were developed to carcinoma;6 cases were severe dysplasia and carcinoma in situ,all 6 cases were recurrenced and 5 cases were developed to carcinoma.Conclusion The histopathological classi-fication is predictive factor for the risk of recurrence and malignant transformation in vocal cord leukoplakia.
出处
《中国基层医药》
CAS
2016年第18期2721-2723,共3页
Chinese Journal of Primary Medicine and Pharmacy
基金
浙江省温岭市科技计划项目（2015C311036
2012WLCD0088）
关键词
声带白斑
病理
复发
癌变
Leukoplakia,vocal cord
Histopathological feature
Recurrence
Carcinogenesis
