摘要
目的探讨老年2型糖尿病（T2DM）患者认知障碍的危险因素。方法选择2015-02~2016-01入住我院内分泌科的T2DM患者210例,根据蒙特利尔认知评估（MoCA）测定结果分为认知障碍（CI）组（n=52）和认知功能正常（non-CI）组（n=158）,记录并比较了两组患者的人口学信息、体格检查和实验室检查结果、伴发疾病及糖尿病并发症情况。结果两组患者的年龄、受教育程度、糖尿病病程、糖化血红蛋白（Hb A1c）、空腹胰岛素水平比较有统计学差异（P〈0.05）;认知障碍组合并卒中、高血压及每日运动〈0.5 h患者比例显著高于认知功能正常组（P〈0.05）。多因素Logistic回归分析显示年龄、每日运动〈0.5 h、HbA1c、卒中是认知障碍的危险因素（P〈0.05）。结论老年2型糖尿病患者年龄、HbA1c、合并卒中、每日运动〈0.5 h可能是认知障碍的危险因素。
Objective To explore the risk factors associated with the cognitive impairment in the elderly patients with type 2 diabetes mellitus（T2DM）. Methods A total of 210 hospitalized patients with T2DM in the department of endocrinology from February2015 to January 2016 were enrolled in the study and were divided into cognitive impairment group（ n = 52） and non-cognitive impairment group （ n = 158） according to the Montreal cognitive assessment （MoCA） scores. The data of demographic, physical examination and laboratory tests, concomitant diseases and complications of diabetes were collected. Results There was significant difference in the age, education level, duration of T2DM, levels of HbA1 c and fasting insulin between the two groups （P 〈 0.05）. The proportions of patients with stroke, hypertension and daily exercise less than 0.5 h were significantly higher in cognitive impairment group than in non-cognitive impairment group （P 〈 0.05）. Logistic regression analysis showed that age, daily exercise 〈 0.5 h, HbA1 c and stroke were risk factors for cognitive impairment （P〈 0.05）. Conclusion Age, daily exercise 〈 0.5 h, HbA1 c, stroke may be risk factors for cognitive impairment.
出处
《山西医科大学学报》
CAS
2016年第8期747-750,共4页
Journal of Shanxi Medical University
关键词
2型糖尿病
认知障碍
危险因素
type 2 diabetes mellitus
cognitive impairment
risk factor
