摘要
目的分析糖尿病肾病患者泌尿系感染病原菌的耐药性,以提高抗菌药物的治疗效果、防止耐药菌株不断产生。方法选取2013年1月-2015年6月医院58例糖尿病肾病合并泌尿系感染患者为研究对象,经过标本采集、病原菌培养、鉴定菌种种类,并进行相应的药敏试验,数据采用SPSS 18.0软件进行统计分析。结果糖尿病肾病合并泌尿系感染58例患者送检标本,共分离出46株病原菌,以革兰阴性菌为主,共28株占60.87%;大肠埃希菌、肺炎克雷伯菌对亚胺培南耐药率均为0;表皮葡萄球菌、金黄色葡萄球菌对头孢曲松耐药率较低,均<20.0%。结论糖尿病肾病患者泌尿系感染病原菌较多,病原菌对不同的抗菌药物耐药性不同,及时监测病原菌种类、分布及耐药性是十分必要的,有利于抗菌药物的治疗效果提高及防止耐药菌株产生。
OBJECTIVE To analyze the drug resistance of pathogens in urinary system infection in patients with diabetic nephropathy,in order to improve the therapeutic effect of antibiotics and prevent the constantly producfion of drug-resistant strains.METHODS A total of 58 cases of diabetic nephropathy with urinary system infection treated in the hospital were selected.The specimen collection,bacterial culture,identification of bacteria species,and the corresponding sensitivity test were carried out.The data were analyzed by SPSS 18.0.RESULTS Totally 46 strains of pathogens were isolated from 58 cases of patients with diabetic nephropathy and urinary system infection,with the majority of 28 strains of gram-negative bacteria,accounted for 60.87%.The drug resistance of Escherichia coli and Klebsiella pneumoniato imipenem were all 0,and the drug resistance of Staphylococcus epidermidis and Staphylococcus aureus to ceftriaxone were low,less than 20%.CONCLUSIONThere are many kinds of urinary system infection pathogens in patients with diabetic nephropathy,and different pathogens have different drug resistance.It is necessary to timely monitor the pathogens species,distribution and drug resistance,which can help to improve the treatment efficacy and prevention of the constantly produce of drug-resistant strains.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第15期3433-3435,共3页
Chinese Journal of Nosocomiology
基金
天津市卫生局科技基金资助项目(2012KR13)
关键词
糖尿病肾病
泌尿系感染
耐药性
Diabetic nephropathy
Urinary system infection
Drug resistance
