摘要
目的研究高血压脑出血患者泌尿系统感染血清及尿液炎性指标的变化,为提高治愈率提供参考依据。方法选取2014年12月-2015年12月医院诊治42例高血压脑出血泌尿系统感染患者为试验组,同期选取42例高血压脑出血未感染患者为对照组,对两组患者治疗前后不同时间点血清、尿液炎性指标进行测定,分析高血压脑出血泌尿系统感染患者血清及尿液炎性相关指标的变化,数据采用SPSS 18.0软件进行统计分析。结果试验组患者降钙素原(PCT)及C-反应蛋白(CRP),显著高于对照组(P<0.05);两组患者治疗前白细胞介素-6(IL-6)、IL-2以及肿瘤坏死因子-α(TNF-α),显著高于对照组(P<0.05);试验组治疗后IL-6、IL-2以及TNF-α与对照组相比,差异无统计学意义。结论高血压脑出血泌尿系统感染患者血清及尿液炎性相关指标变动较大,应根据检测结果采取有效措施治疗。
OBJECTIVE To study the changes of serum and urine inflammatory indicators of urinary tract infected patients with hypertensive cerebral hemorrhage,in order to provide evidence for improvement of the cure rate.METHODS A total of 42 cases of hypertensive cerebral hemorrhage with urinary tract infections in hospital from Dec.2014 to Dec.2015 were selected as test group,and 42 cases of hospitalized hypertensive cerebral hemorrhage patients without infection at the same period were selected as control group.The serum and urine inflammatory indicators of the two groups of patients were measured at different time points before and after treatment,and the changes of serum and urine inflammatory related indicators of urinary tract infected patients with hypertensive cerebral hemorrhage.The data were analyzed by SPSS 18.0.RESULTS The PCT and CRP levels of test group were significantly higher than those of control group（P〈0.05）.The IL-6,IL-2and TNF-αlevels of the two group before treatment were significantly higher than those of control group（P〈0.05）.The IL-6,IL-2and TNF-αlevels of test group had no significant difference compared with those of control group.CONCLUSIONThe serum and urine inflammatory indicators of urinary tract infected patients with hypertensive cerebral hemorrhage have great changes,and effective measures should be taken for treatment based on test results.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第15期3417-3419,共3页
Chinese Journal of Nosocomiology
基金
河南省科技厅基金资助项目(20114015)
关键词
高血压
脑出血
泌尿系统感染
血清
尿液
炎性指标
Hypertension
Cerebral hemorrhage
Urinary tract infection
Serum
Urine
Inflammatory indicators
