摘要
目的探讨上呼吸道感染与冠心病心血管事件的相关性,为临床冠心病诊治提供参考依据。方法选择医院2014年10月-2015年10月冠心病合并上呼吸道感染的住院患者60例作为感染组,选择同期无上呼吸道感染的冠心病住院患者60例作为对照组;比较两组患者心血管事件发生情况,探讨冠心病死亡的影响因素,数据采用SPSS 17.0软件进行统计分析。结果感染组患者心力衰竭发生率为11.7%、病死率为16.7%,高于对照组1.7%、6.7%(P<0.05);冠心病患者患上呼吸道感染、急性心肌梗死和陈旧性心肌梗死病史是其死亡的独立影响因素,其OR值分别为3.8、4.3和15.5。结论上呼吸道感染降低冠心病患者血清高密度脂蛋白胆固醇和低密度脂蛋白胆固醇,增加血清C-反应蛋白水平,增加冠心病患者心力衰竭及病死率,是其死亡的独立危险因素。
OBJECTIVE To analyze the correlation of upper respiratory tract infection and coronary heart disease and cardiovascular events,so as to provide evidence for coronary heart disease diagnosis and treatment.METHODS A total of 60 cases of patients with coronary heart disease combined upper respiratory tract infection in our hospital from Oct.2014 to Oct.2015 were selected as infection group,another 60 patients with coronary artery disease but no upper respiratory tract infection in the same period as control group.The incidence of cardiovascular events was compared.The influencing factors of coronary heart disease mortality was explored.SPSS17.0was used for statistic analysis.RESULTS The incidence of heart failure was 11.7% and death incidence was16.7%in infection group which were higher than the incidence of heart failure 1.7% and death incidence 6.7%in control group（P〈0.05）.Upper respiratory tract infection,acute myocardial infarction and old myocardial infarction were independent risk factors of death to patients with coronary heart disease,and the OR values were 3.8,4.3and 15.5.CONCLUSION Upper respiratory tract infection can decrease the serum high-density lipoprotein cholesterol and low density lipoprotein cholesterol in coronary heart disease patients and increase serum C-reactive protein levels,which also can increase the incidence of heart failure and death of coronary heart disease patients.Upper respiratory tract infection is an independent risk factor for coronary heart disease death.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第15期3412-3413,3416,共3页
Chinese Journal of Nosocomiology
基金
国家自然科学基金资助项目(81270659)
关键词
上呼吸道感染
冠心病
心血管事件
Upper respiratory infection
Coronary heart disease
Cardiovascular events
