摘要
目的研究病毒性心肌炎病原学特征,为临床诊断和合理治疗提供参考依据。方法选取医院2010年2月-2014年9月210例病毒性心肌炎患儿为观察组,同期选择健康体检儿童210名为对照组,比较两组心肌酶水平变化,数据采用SPSS 18.0软件进行统计分析。结果观察组患儿中共分离出病毒210株,以RNA病毒为主,共119株占56.7%;观察组患儿心电图出现异常,以QT间期延长为主,共26例占12.4%;观察组患儿血清肌酸激酶、肌酸激酶同工酶及乳酸脱氢酶和α-羟丁酸水平显著高于对照组,差异均有统计学意义(P<0.05)。结论病毒性心肌炎患儿病原菌以RNA病毒为主,且存在明显的心电图和心肌酶异常。
OBJECTIVE To analyze the pathogenic features of viral myocarditis,so as to provide the reference for clinical diagnosis and treatment.METHODS A total of 210 cases of viral myocarditis patients in our hospital from Feb.2010 to Sep.2014 were enrolled in this study as observation group and another 210 cases of healthy subjects at the same period in our hospital were taken as control group.The changes of myocardial enzymes levels were compared between these two groups.SPSS 17.0was used for statistic analysis.RESULTS A total of 210 strains of pathogens isolated from the patients in observation group,mainly 119 strains of RNA virus（56.7%）.The patients in observation group also showed abnormal characteristics in ECG,mainly from 26cases（12.4%）of patients with lengthened interval in QT.The creatine kinase,creatine kinase isozyme,lactate dehydrogenase andα-hydroxybutyric acid in serum from observation group were significantly higher than that in control group（P〈0.05）.CONCLUSIONRNA virus is the main pathogen in children with viral myocarditis with obvious abnormal ECG and myocardial enzymes.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第15期3406-3408,共3页
Chinese Journal of Nosocomiology
基金
河南省科技攻关计划基金资助项目(112102310265)
