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慢性心力衰竭患者医院感染临床特点与预防研究 被引量:7

Clinical characteristics and prevention of nosocomial infections in patients with chronic heart failure
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摘要 目的分析慢性心力衰竭患者医院感染发生情况、病原菌分布特点及其相关危险因素,并提出相应的干预措施。方法选取2013年2月-2015年5月医院收治的慢性心力衰竭患者500例为研究对象,对慢性心力衰竭合并医院感染发生情况、病原菌的分布特点进行分析,相关危险因素进行logistic回归分析,数据采用SPSS 18.0软件进行统计分析。结果 500例慢性心力衰竭患者发生医院感染20例,感染率为4.00%;共检出48株病原菌,以革兰阴性菌为主占77.09%,其次为革兰阳性菌占16.67%、真菌占6.25%;多因素logistic回归分析显示,慢性心力衰竭患者年龄、心功能分级、合并基础疾病、侵入性操作、预防使用抗菌药物及住院时间是发生医院感染的独立危险因素(P<0.05)。结论慢性心力衰竭患者引发医院感染的危险因素较多,应根据相应危险因素制定对应干预措施并积极实施。 OBJECTIVE To analyze the incidences of nosocomial infections in patients with chronic heart failure,the distribution characteristics of pathogenic bacteria and the related risk factors,and to propose the corresponding intervention measures.METHODS A total of 500 patients with chronic heart failure in our hospital from Feb.2013 to May 2015 were selected as the study objects.The occurrence of nosocomial infections in patients with chronic heart failure,and the distribution characteristics of pathogenic bacteria were analyzed.The related risk factors were analyzed by logistic regression analysis.Data were analyzed by SPSS 18.0.RESULTS A total of 20 cases from 500 cases of chronic heart failure patients got nosocomial infections,and the infection rate was 4%.There were 48 strains of pathogens detected,mainly gram-negative bacteria,accounting for 77.09%,followed by grampositive bacteria 16.66%,fungi 6.25%.By logistic regression analysis,the independent risk factors of nosocomial infections in patients with chronic heart failure were age,heart function classification,combined with basic diseases,invasive operation,antibiotic prophylaxis and the time of hospitalization(P〈0.05).CONCLUSION There are many risk factors to cause nosocomial infections in patients with chronic heart failure,according to which the corresponding interventions should be implemented actively,in order to reduce the incidence of nosocomial infections.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2016年第15期3403-3405,共3页 Chinese Journal of Nosocomiology
基金 重庆市医学科研计划基金资助项目(2013-2-196) 重庆市卫生计生委医学科研基金资助项目(2015ZBXMO43)
关键词 慢性心力衰竭 医院感染 临床特点 干预对策 Chronic heart failure Nosocomial infection Clinical characteristics Intervention strategy
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