摘要
目的探讨上呼吸道感染对嗅觉功能障碍患者的影响,为临床提供理论依据。方法选择2010年1月-2015年6月在医院就诊的晚期喉癌或下咽癌术后咽瘘患者515例,作为研究组,选择100名健康体检者作为对照组,检测两组入选者嗅觉识别阈值分数、嗅球体积、嗅沟深度。结果研究组患者中,31例发生上呼吸道感染,感染率为6.02%;上呼吸道感染患者嗅觉识别阈值分数为(2.87±0.33)分,未感染患者嗅觉识别阈值分数为(0.89±0.21)分(P<0.05),对照组嗅球体积高于研究组,研究组未感染患者嗅球体积大于感染患者,差异有统计学意义(P<0.05),两组嗅沟深度比较差异无统计学意义。结论上呼吸道感染导致患者嗅球体积缩小,增加嗅觉识别阈值分数,降低患者的嗅觉功能。
OBJECTIVE To explore the effect of upper respiratory tract infection on olfactory dysfunction,so as to provide theoretical basis for clinical.METHODS A total of 515 cases of patients with advanced laryngeal carcinoma and laryngeal carcinoma from Jan.2010 to Jun.2015 were selected as research group,another 100 cases of healthy persons were selected as control group.The odor threshold value,olfactory bulb volume,and olfactory groove depth of the two groups were detected.RESULTS Totally 31 cases of patients had upper respiratory tract infection in research group,with the infection rate of 6.02%,their odor threshold value was（2.87±0.33）,and the odor threshold value of uninfected patients was（0.89±0.21）（P〈0.05）.The volume of olfactory bulb in control group was higher than that in research group,and the volume of olfactory bulb of uninfected patients was higher than that of infected patients in research group（P〈0.05）.The olfactory groove depth of the two groups had no difference.CONCLUSION Upper respiratory tract infection can reduce the size of olfactory bulb,increase the odor threshold value and reduce the olfactory function in patients.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第15期3395-3397,共3页
Chinese Journal of Nosocomiology
基金
山东省自然科学基金资助项目(Y2006C02)
关键词
上呼吸道感染
嗅觉功能
障碍
Upper respiratory tract infection
Olfactory function
Barrier
