摘要
目的探讨肝内复发性肝细胞癌(肝癌)的治疗方法和再手术切除的疗效。方法对1995年1月至2010年6月收治的124例肝癌术后肝内复发病例的临床资料进行回顾性分析。结果1、3、5年生存率再手术组分别为73.3%、33.6%、18.3%,局部治疗组分别为44.1%、11.6%、7.0%,保守治疗组仅5例存活超过1年。早期复发病例1、3、5年生存率分别为46.3%、14.7%、7.4%,晚期复发病例1、3、5年生存率分别为69.0%、37.9%、24.1%。结论肝癌术后肝内复发应采取积极的治疗,再手术切除是最有效的治疗方法;对不能再手术的病例,介入为主的综合治疗可提高生存率。
Objective To investigate techniques and efficacy of re-resection for intrahepatic re- current hepatocellular carcinoma （HCC）. Methods From Jan. 1995 to June 2010, the clinical and fol- low-up data of 124 patients with intrahepatic recurrent HCC were analyzed retrospectively. Results The overall 1-, 3-, and 5-year survival rate in re-resection group was 73. 3%, 33.6%, and 18. 3% re- spectively, and 44. 1 %, 11.6%, and 7. 0% respectively in local treatment group. Only 5 cases sur- vived over one year in conservative treatment group. The overall 1-, 3-, and 5-year survival rate in early recurrent group was 46. 3%, 14. 7%, and 7. 4%/%0 respectively, and 69. 0%, 37. 9%, and 24. 1% respectively in later recurrenet group. Conclusions For patients with intrahepatic recurrent HCC, ac- tive treatment should be adopted, and re-resection is the most effective treatment. For unresectable cases, comprehensive treatment based on interventional therapy could improve survival rate.
出处
《腹部外科》
2016年第3期209-213,共5页
Journal of Abdominal Surgery
关键词
肝细胞癌
复发
再手术
Hepatocellular carcinoma
Recurrence
Re-resection
