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3种难治性子宫出血治疗方案临床对比研究 被引量:7

Three therapeutic schemes for refractory uterine bleeding:a clinical comparative study
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摘要 目的对比分析宫腔填塞术、子宫动脉结扎术及介入栓塞术3种治疗方案治疗难治性分娩后子宫出血的临床效果及安全性差异。方法选取2010年1月至2015年5月在陕西中医药大学第二附属医院治疗的难治性分娩后子宫出血患者共170例,根据治疗方案不同分为宫腔填塞术组(A组,n=70)、子宫动脉结扎术组(B组,n=50)及介入栓塞术组(C组,n=50),3组患者一般资料比较差异无统计学意义(P>0.05)。比较3组患者止血效果、术中出血量、分娩后出血量、止血时间、手术时间及子宫切除率、术后并发症发生率等。结果 C组患者止血效果显著优于A、B组(P<0.05),术中出血量、分娩后出血量、止血时间及手术时间均显著优于A、B组(P<0.05),子宫切除率显著低于A、B组(P<0.05);3组患者术后并发症发生率差异无统计学意义(P>0.05)。结论子宫动脉介入栓塞术治疗难治性分娩后子宫出血与宫腔填塞术、子宫动脉结扎术相比,可快速有效控制出血,缩短治疗时间,降低子宫切除概率,且未增加术后并发症发生风险。 Objective To compare the clinical effects and safety of three therapeutic schemes, i.e. uterine cavity packing, uterine artery ligation and interventional embolization, for refractory post-delivery uterine bleeding. Methods A total of 170 patients with refractory post-delivery uterine bleeding, who were admitted to the Second Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine during the period from January 2010 to May 2015, were enrolled in this study. According the the therapeutic scheme, the patients were divided into group A ( n = 70, receiving uterine cavity packing) , group B ( n = 50, receiving uterine artery ligation) and group C (n = 50, receiving interventional embolization). No statistically significant differences in general data existed between each other among the three groups (P 〉 0.05 ). The hemostatic effect, the volume of intraoperative blood loss, the volume of post-delivery bleeding, hemostasis time, operation time, hysterectomy rate, and the incidence of postoperative complications, etc. were compared among the three groups. Results The hemostatic effect of group C was significant better than that of group A and group B ( P〈 0.05). The volume of intraoperative blood loss, the volume of post-delivery bleeding, the hemostasis time and the operation time in group C were strikingly less than those in both group A and group B (P〈0.05). The hysterectomy rate of group C was obviously lower than that of both group A and group B ( P 〈 0.05 ). No statistically significant differences in the incidence of postoperative complications existed between each other among the three groups (P〉 0.05 ). Conclusion Compared with uterine cavity packing and uterine artery ligation treatment for refractory post-delivery uterine bleeding, interventional embolization of uterine artery can quickly and effectively control the bleeding, shorten the treatment time and reduce the hysterectomy rate, while this technique does not increase the risk of postoperative complications.
出处 《介入放射学杂志》 CSCD 北大核心 2016年第7期586-589,共4页 Journal of Interventional Radiology
关键词 宫腔填塞 子宫动脉结扎 动脉介入栓塞 子宫出血 疗效 安全性 uterine cavity packing uterine artery ligation interventional artery embolization uterine bleeding therapeutic effect safety
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