摘要
目的 探讨全切片扫描图像技术在浆膜腔积液细胞块初始诊断中的可行性。方法 回顾成都市第一人民医院病理科2015年1~12月318例浆膜腔积液细胞块病理资料,采用优纳第四代全自动数字切片扫描系统扫描玻片,存入电脑。所有玻片均由同一位病理主治医生独立重新阅片分析。观察者先进行原始玻片传统光学显微镜判读,5周后再于电脑上判读数字切片。阅片结束后,计算分析光学显微镜上判读与电脑数字切片判读的的可重复性。结果 全切片扫描图像诊断与传统光学显微镜诊断的,Kappa值0.91。所有的诊断差异性出现在可疑肿瘤病例,在良性与恶性病例之间没有诊断差异性。结论数字切片扫描图像技术可用于细胞块初始诊断。
Objective To investigate the feasibility of whole slide imaging （ WSI） of serous effusion cell blocks for the prima-ry diagnosis.Methods Serous effusion cell blocks from 318 cases between January 2015 and December 2015 at our department were retrospectively reviewed .Each slide was digitally scanned by UNIC fourth generation digital section scanning system and the images were stored in a shared file .All slices were independently reviewed by the same pathologists .The observers first reviewed the glass slides under conventional microscopy （CM） and then reviewed the digital images in an interval of 5 weeks.After finishing all cases,re-producibility of WSI versus CM were analyzed .Results The diagnostic reproducibility for WSI versus CM was 95% CI （ 0.93 ~0.97 ） .κ=0.91 .All diagnostic disagreements were found in suspicious malignancy .There was no intra observer disagreement in the diagnosis of benign versus malignant diseases .Conclusion WSI could be used for the initial diagnosis of serous effusion cell blocks .
出处
《实用医院临床杂志》
2016年第4期89-92,共4页
Practical Journal of Clinical Medicine
