摘要
目的:探讨黄芪口服液辅助化疗治疗老年肺癌的临床疗效及对免疫功能的影响.方法:选取成都中医药大学附属医院2012-08/2014-08就诊的80例肺癌患者作为研究对象,随机分为对照组(n=40,单纯化疗组)和实验组(n=40,黄芪口服液联合化疗组).比较两组患者治疗后的近期疗效、治疗前后免疫功能及生活质量的变化.结果:两组患者的RR、DCR相比,差异均无统计学意义(P>0.05).实验组患者6个月、12个月及18个月的生存率均明显高于对照组,差异具有统计学意义(P<0.05).实验组CD3^+、CD4^+、CD8^+及NK细胞的活性比对照组明显增高,差异具有统计学意义(P<0.05).结论:黄芪口服液辅助化疗能够有效改善老年肺癌患者的免疫功能,提高生活质量,延长生存期.
AIM： To investigate the efficacy of Huang-qi oral liquid assisted with chemotherapy in elderly patients with lung cancer. METHODS： A total of 80 elderly patients with lung cancer admitted into the Teaching Hospital of Chengdu University of TCM from August 2012 to August 2014 were selected as study objects and were randomly divided into experiment group（ n = 40,treated with Huang-qi oral liquid assisted with chemotherapy） and control group（ n = 40,treated with chemotherapy alone）. The short-term response was compared between the two groups. The changes of immune function and quality of life before and after treatment in the two groups were compared. RESULTS： There was no statistically significant difference in RR or DCR of the two groups（ P0.05）. The survival rates of 6 months,12 months and18 months of the experimental group were significantly higher than those of the control group,there was statistically significant difference（ P 0. 05）. The CD3~＋,CD4~＋,CD8~＋and NK cells activity of the experimental group were significantly higher than the control group,there was statistically significant difference（ P 0. 05）.CONCLUSION： In the treatment of geriatric lung cancer,the combination of chemotherapy with Huang-qi oral liquid is significantly helpful for improving immunity and lengthening the lives of patients.
出处
《转化医学电子杂志》
2016年第5期1-3,共3页
E-Journal of Translational Medicine
关键词
黄芪口服液
辅助化疗
老年肺癌
疗效
免疫功能
Huang-qi oral liquid
assisted with chemotherapy
geriatric lung cancer
efficacy
immune function
