摘要
目的探讨胰头癌及壶腹周围癌老年患者施行胰十二指肠切除术的安全性及临床疗效。方法对2007年2月至2015年6月于我科施行胰十二指肠切除术的69例临床资料进行回顾性分析。结果术前老年组患者(≥65岁,38例)较中青年组患者(<65岁,31例)基础疾病多(P<0.05),前白蛋白明显低(P<0.05)。所有患者均成功施行Whipple手术。两组患者术中出血量、术中输血量、术后并发症发生率均无统计学差异(P>0.05);老年组手术时间、术后住院时间较长(P<0.05)。两组患者均顺利恢复,无围手术期死亡,术后1年、3年生存率无统计学差异(P=0.26)。结论针对胰头癌及壶腹周围癌的老年患者,施行胰十二指肠切除手术是安全、可行的,其临床疗效与中青年患者无差异。
Objective To investigate the clinical efficacy and safety ofpancreaticoduodenectomy for treating carcinoma of head of pancreas and periampuUary carcinoma in elderly. Methods Sixty-nine patients underwent pancreaticoduodenectomy in our department from Feb. 2007 to Jun. 2015 were retrospectively analyzed. Results Compared with younger group （〈65 years, n=31）, underlying diseases were more （P〈0.05）, and prealbumin level was lower （P〈0.05） in elderly group （〉65 years, n=38）. All 69 patients were successfully undergone Whipple operation. Difference of bleeding volume, blood transfusion volume in surgery, and complications after surgery had no statistically significance （/〉〉0.05） between two groups. Operating time and postoperative hospitalization were longer in elderly group （P〈0.05）. All patients recovered smoothly, no death occurred in perioperative pe- riod. There was no significant difference of survival rates after 1 year, 3 years postoperative between two groups （P=0.26）. Conclusion For elderly patients with carcinoma of head of pancreas and periampullary carcinoma, pancreaticoduodenectomy is safe and feasible operation method; the clinical effect has no difference for the younger and middle age patients.
出处
《肝胆胰外科杂志》
CAS
2016年第3期181-184,共4页
Journal of Hepatopancreatobiliary Surgery
关键词
老年患者
胰十二指肠切除术
胰头癌
壶腹周围癌
elderly patients
pancreaticoduodenectomy
carcinoma of head of pancreas
periampullary carcinoma
