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颅内大动脉狭窄或闭塞与自发性大脑凸面蛛网膜下腔出血的相关性 被引量:1

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摘要 目的探讨颅内大动脉狭窄或闭塞导致自发性大脑凸面蛛网膜下腔出血(cSAH)的病理机制及影像学特征。方法回顾自2013-01-2015-06就诊于南阳市中心医院神经科的11例临床表现为cSAH的颅内大动脉狭窄或闭塞患者的病例资料,分析其人口学特征、临床表现、影像学特征,探讨其病理机制。结果共纳入11例患者,男8例,女3例,中位数年龄62岁。所有患者均有长期高血压病史,未进行规范降压治疗。临床症状:类似TIA者7例(63.6%),不同程度持续性神经功能缺损症状3例(27.3%),癫痫发作1例(9.1%),其中伴有轻中度头痛4例(36.4%)。影像结果:所有患者头CT均表现为出血局限于一个或几个脑沟内,DSA检查未发现动脉瘤,表现为单侧或双侧前循环大血管狭窄或闭塞,其中烟雾病2例,单侧大血管狭窄/闭塞9例,包括ICA闭塞1例,MCA闭塞7例及MCA重度狭窄1例。所有患者的DSA均可见丰富的侧支循环,软脑膜吻合支开放最常见。结论 (1)cSAH的临床表现具有多样性,缺乏特异性,以发作性症状最多见;(2)颅内大血管重度狭窄/闭塞是cSAH的重要病因之一,并以MCA为主,软脑膜吻合血管破裂是导致cSAH的发病原因;(3)血压的高位变异波动是导致软脑膜血管破裂的直接诱因。
出处 《中国实用神经疾病杂志》 2016年第5期29-31,共3页 Chinese Journal of Practical Nervous Diseases
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