摘要
目的:了解广西科技大学第一附属医院(以下简称"我院")药品不良反应(adverse drug reaction,ADR)的发生特点,为临床合理用药提供参考。方法:对我院2014年收集到的202例ADR报告,按患者性别、年龄、用药情况、累及器官和(或)系统以及临床表现等进行统计、分析。结果:202例ADR患者中,>45岁的有143例,占70.79%。ADR涉及的药品有132种,抗菌药物居首位,其次是中药制剂;给药途径以静脉滴注为主;临床表现以皮肤及其附件损害最为常见。结论:ADR发生与多种因素有关,医院应进一步完善医、药、护合作的ADR监测体系,加强对老年患者的监控,尽量减少静脉途径给药,加强临床药师的培养,充分发挥临床药师在用药监护方面的作用,合理用药,以减少或避免ADR的发生。
To investigate the characteristics of adverse drug reaction（ADR） in the First Affiliated Hospital of Guangxi University of Science and Technology（hereinafter referred to as＂our hospital＂）,so as to provide reference for the rational drug use in clinic.METHODS：202 cases of ADR reports in 2014 were collected,statistical analysis was conducted on the patients＇ gender,age,administration,involved organs or systems and clinical manifestations,etc.RESULTS：Of the 202 cases,143 case were over 45 years old,accounting for 70.79%.A total of 132 drugs wereinvolved,antibiotics took the lead,followed by traditional Chinese medicine preparation;the main route of administration was intravenous drip;and the clinical manifestations were mainly skin and its accessories damage.CONCLUSIONS：The occurrence of ADR is related to various factors.Hospitals should further improve the monitoring system in cooperation of medicine,pharmacy and nursing,strengthen the monitoring of elderly patients with ADR,reduce the route of administration by intravenous drip,strengthen the train in clinical pharmacists,exert the role of clinical pharmacists in drug monitoring and promote rational drug use,so as to reduce or avoid the occurrence of ADR.
出处
《中国医院用药评价与分析》
2016年第4期537-539,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
报告分析
合理用药
Adverse drug reactions
Analysis of reports
Rational drug use
