摘要
目的评价间苯三酚联用黄体酮治疗妊娠合并肾绞痛的效果和安全性。方法60例妊娠期肾绞痛患者随机分为2组，每组30例，观察组静滴间苯三酚120mg，对照组静滴山莨胆碱10mg，两组均同时给予黄体酮40mg肌注，观察两组患者1h后的解痉镇痛效果、不良反应和6h内的疼痛再发率。结果观察组和对照组治疗的有效率分别为93．3％、60％；6h内疼痛再发率分别为14．3％、55．6％；不良反应发生率分别为16．7％、76．7％。两组问的有效率、再发率及不良反应发生率差异均有统计学意义（P〈0．05）。结论间苯三酚联用黄体酮治疗妊娠合并肾绞痛疗效确切，不良反应发生率及疼痛再发率低，且有助于安胎，值得临床应用。
Objective To evaluate the efficacy and safety of phloroglucinol combined with progesterone in pregnancy patients with renal colic. Methods 60 pregnancy patients with renal colic were randomly divided into two groups with 30 patients in each group. Pholroglucinol 120 mg combined with progesterone 40 mg were used in treat- ment group. Anisodamine 10 mg combined with progesterone 40 mg were used in control group. Spasmolysis analgesic effects and adverse reactions after 1 h and 6 h recurrence rates of pain were observed. Results The effective rates in the treatment group and control group were 93.3% and 60% respectively. Pain recurrence rates within 6 h were 14.3% and 55.6% respectively. Adverse reaction rates were 16.7% and 76.7% respectively. There were significant differences in effective rates, pain recurrence rates and adverse reaction rates between the two groups（ P 〈 0. 05 ）. Conclusions Efficacy of phloroglucinol combined with progesterone is good in pregnancy patients with renal colic because pain recurrence rates and adverse reaction rates are low.
出处
《医学新知》
CAS
2016年第2期113-115,共3页
New Medicine
关键词
间苯三酚
黄体酮
妊娠
肾绞痛
Phloroglucinol
Progesterone
Pregnancy
Renal colic
