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冻融周期中单个优质囊胚移植的应用 被引量:4

The Application of Vitrified Single High-Quality Blastocyst Transfer
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摘要 目的探讨冻融周期第5天单个优质囊胚复苏后移植的临床价值。方法回顾性分析2013年1月至2014年12月在我院接受首次复苏优质囊胚移植治疗的患者临床资料,按移植胚胎数分为单囊胚移植组(n=65)、双囊胚移植组(n=240),比较两组的妊娠率、种植率、多胎率、移植胚胎利用率。结果两组的临床妊娠率差异无统计学意义(P>0.05);单囊胚移植组种植率显著高于双囊胚移植组,差异有统计学意义(P<0.01);单囊胚移植组移植胚胎利用率显著高于双囊胚移植组,差异有统计学意义(P<0.05);单囊胚移植组多胎率显著低于双囊胚移植组,差异有统计学意义(P<0.01)。结论冻融周期行单个优质囊胚移植可以保证临床妊娠率,明显降低多胎率,提高胚胎利用率,获得较满意的临床结局。 Objective To explore the clinical value of day 5 single high-quality frozen-thawed blastocyst transfer. Methods Retrospectively analyze patients' clinical documents on the first time treatment of high quality frozen-thawed blastocyst transfer in our hospital during Jan,2013 to Dec,2014.Compare the clinical pregnancy rate,implantation rate,multiple pregnancy rate and embryos utilization rate of the single blastocyst transfer group( n = 65) and double blastocyst transfer group( n = 240),which were divided based on the number of embryos. Results There was no statistical difference between two groups on the clinical pregnancy rate( P〈0.05).but the implantation rate of single blastocyst group was higher than double blastocyst group( P〈0.01).The embryos utilization rate of single blastocyst group was higher than double blastocyst group( P〈0.05). The multiple pregnancy rate of single blastocyst group was lower than double blastocyst group( P〈0.01). Conclusion Single high-quality frozen-thawed blastocyst transfer can ensure clinical pregnancy rate,reduce multiple pregnancy rate and improve the embryos utilization rate.It achieved better clinical result.
出处 《中南医学科学杂志》 CAS 2016年第2期195-197,208,共4页 Medical Science Journal of Central South China
关键词 冻融单囊胚移植 临床妊娠率 多胎率 胚胎利用率 single frozen-thawed blastocyst transfer clinical pregnancy rate multiple pregnancy rate embryos utilization rate
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参考文献9

  • 1Pfeifer S,Fritz M,Goldberg J.Blastocyst culture and transfer in clinical-assisted reproduction:a committee opinion.[J].Fertil Steril,2013,99(3):667-672.
  • 2Qin J,Wang H,Sheng X,et al.Pregnancy-related complications and adverse pregnancy outcomes in multiple pregnancies resulting from assisted reproductive technology:a meta-analysis of cohort studies[J].Fertil Steril,2015,103(6):1492-1508.
  • 3Chambers GM,Ledger W.Economic implications of multiple pregnancy following assisted reproductive technologies[J].Seminars Fetal Neonatal Medical,2014,19(4):254-261.
  • 4López-Regalado ML,Clavero A,Gonzalvo MC,et al.Randomised clinical trial comparing elective single-embryo transfer followed by single-embryo cryotransfer versus double embryo transfer[J].European Journal of Obstet Gynecol Reprod Biollgy,2014,178:192-198.
  • 5Pfeifer S,Fritz M,Goldberg J.Criteria for number of embryos to transfer:a committee opinion[J].Fertil Steril,2013,99:44-46.
  • 6Chai J,Yeung TW,Lee VC,et al.Live birth rate,multiple pregnancy rate,and obstetric outcomes of elective single and double embryo transfers:Hong Kong experience[J].Hong Kong Medical Journal,2014,20(2):102-106.
  • 7Devine K,Connell MT,Richter KS,et al.Single vitrified blastocyst transfer maximizes live born children per embryo while minimizing preterm birth[J].Fertil Steril,2015,103(6):1454-1460.
  • 8Jones HW Jr,Oehninger S,Bocca S,et al.Reproductive efficiency of human oocytes fertilized in vitro[J].Facts Views Vis Obgyn,2010,2(3):169-171.
  • 9Kanter JR,Boulet SL,Kawwass JF,et al.Trends and correlates of monozygotic twinning after single embryo transfer[J].Obstetric Gynecology,2015,125(1):111-117.

同被引文献32

  • 1Gardner DK, Schoolcraft WB, Wagley L, et al. A prospective randomized trial ofblastocyst culture and transfer in in-vitro fertilization. Hum Reprod, 1998, 13(12):3434-40.
  • 2Milingos DS, Bhattacharya S. Single embryo tranfer. Obstet Gynecol Reprod Med, 2009, 19(8):229-31.
  • 3Sharara FI, Abdo G, Incidence of monozygotic twins in blastocyst and cleavage stage assisted reproductive technology cycles. Fertil Steril, 2010, 93(2):642-5.
  • 4Ishihara O, Araki R, Kuwahara A, et al. Impact of frozen- thawed single-blastocyst transfer on maternal and neonatal outcome: an analysis of 277 042 single-embryo transfer cycles from 2008 to 2010 in Japan. Fertil Steril, 2014, 101 (5):128-33.
  • 5Goto S, Kadowaki T, Tanaka S, et al. Prediction of pregnancy rate by blastocyst morphologi-cal score and age, based on 1 488 single frozen-thawed blastocyst transfer cycles. Fertil Steril, 2011, 95(3):948-52.
  • 6Roy TK, Bradley CK, Bowman MC, et al. Single-embryo transfer of vitrified-warmed blastocysts yields equivalent live-birth rates and improved neonatal outcomes compared with fresh transfers. Fertil Steril, 2014, 101(5): 1294-301.
  • 7Han AR, Park CW, Lee HS, et al. Blastocyst transfer in frozen-thawed cycles. Clin Exp Reprod Med, 2012, 39 (3):114-7.
  • 8Papanikolaou EG, Camus M, Kolibianakis EM, et al. In vitro fertilization with single blastocyst-stage versus single cleavage-stage embroys. N Engl J Med, 2006, 354(11): 1139-46.
  • 9Duncombe GJ, Dickinson JE, Evans SF. Perinatal characteris- tics and outcomes of pregnancies complicated by twin- twin transfusion syndrome. Obstet Gynecol, 2003, 101 (6): 1190-6.
  • 10Papanikolaou EG, Fatemi H, Venetis C, et al. Monozygotic twinning is not increased after single blastocyst transfer compared with single cleavage-stage embryo transfer. Fertil Steril, 2010, 93(2):592-7.

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