摘要
目的探讨过敏性紫癜(HSP)合并肺炎支原体(MP)感染患者血清免疫球蛋白及补体的水平。方法收集我院收治的50例患者为研究对象,对患者的实施MP-IgM抗体检测,25例MP-IgM阳性患者为观察组,25例MP-IgM阴性患者维护对照组,给予全自动生化分析仪器对患儿的血清免疫球蛋白IgG、IgA、IgE、IgM及补体C3、C4各项指标进行检测,观察两组患者的各指标水平变化情况。结果对照组IgE水平明显比对照组高,观察组IgM水平比对照组下降更明显,观察组C3、C4下降水平明显低于对照组,组间比较差异具有统计学意义(P<0.05)。结论 HSP患者MP感染率极高,患儿血清IgA升高或C3降低表示体液免疫参与HSP发病,随着患者被体液免疫功能逐渐紊乱,C4水平明显下降,表明MP感染对引起HSP患儿发生、发展发挥着重要作用。
Objective Allergic purpura（HSP） merger mycoplasma pneumoniae（MP） infection of the patient＇s serum immunoglobulin and complement levels. Methods Collection of 50 patients of our hospital as the research object, on the implementation of the patients with MP-Ig M antibody detection, 25 patients with MP-Ig M as the observation group, control group of 25 patients with MP-Ig M negative maintenance, giving full automatic biochemical analysis instrument to the patient＇s serum immunoglobulin Ig G, Ig A, Ig E, Ig M and detection of the various indicators of C3 and C4 changes observed two groups of the patient＇s level of each index. Results Control group Ig E level is significantly higher than the control group, the observation group Ig M level decreased more obvious than the control group, observation group of C3 and C4 levels decrease significantly lower than the control group, compare the differences between groups with statistical significance（P〈0.05）. Conclusion Children with HSP patients with MP infection rate is extremely high, elevated serum Ig A or C3 said humoral immune to participate in HSP pathogenesis, as was the humoral immune function in patients with disorders, C4 level declined obviously, showed that MP infection in children with HSP plays an important role in the occurrence and development.
出处
《中国医药指南》
2016年第11期12-13,共2页
Guide of China Medicine
关键词
过敏性紫癜
肺炎支原体感染
免疫球蛋白
Allergic purpura
Mycoplasma pneumoniae infection
Immunoglobulin
