摘要
目的观察负压封闭引流术对大面积烧伤创面脓毒症患者的效果,为改善患者预后提供参考依据。方法将2013年1月-2015年6月接收的80例大面积烧伤创面脓毒症患者采用随机数字法分为观察组与对照组,各40例;对照组采用传统方法每日换药,观察组给予负压封闭引流术,比较两组患者指标,数据采用SPSS 17.0软件进行统计分析。结果治疗前,两组患者血乳酸(LA)、C-反应蛋白、降钙素原、肿瘤坏死因子-α及白细胞介素-6水平比较,差异均无统计学意义,治疗15d后,两组患者LA等水平均显著降低,且观察组个指标均显著低于对照组,差异均有统计学意义(P<0.05)。结论对于大面积烧伤创面脓毒症患者,负压封闭引流术能够促进肉芽组织增生、提高植皮术后皮片成活优良率,减轻了患者痛苦,值得临床上推广应用。
OBJECTIVE To observe the effect of vacuum sealing drainage on patients with large area burn wound sepsis so as to improve the prognosis of the patients.METHODS A total of 80 patients with large area burn wound sepsis who were treated from Jan 2013 to Jun 2015 were enrolled in the study and randomly divided into the observation group and the control group,with 40 cases in each.The control group was given the conventional daily drug dressing,while the observation group was treated with vacuum sealing drainage,the indicators were observed and compared between the two groups,and the statistical analysis of data was performed with the use of SPSS 17.0software.RESULTS There was no significant difference in the level of blood lactic acid（LA）,C-reactive protein,procalcitonin,tumor necrosis factor-α,or interleukin-6between the two groups of patients before the treatment.The level of LA of the two groups of patients was significantly reduced after the treatment for 15 days,and the levels of the indicators of the observation group were significantly lower than those of the control group（P〈0.05）.CONCLUSIONAs for the patients with large area burn wound sepsis,the vacuum sealing drainage can promote the proliferation of granulation tissue,raise the rate of good survival of skin graft after skin grafting,and alleviate the pain of the patients,it is worthy to be promoted in the hospital.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第8期1822-1824,共3页
Chinese Journal of Nosocomiology
基金
河南省科技攻关基金资助项目(122102310070)
关键词
烧伤
脓毒症
创面感染
负压封闭引流术
Burn wound
Sepsis
Wound infection
Vacuum sealing drainage
