摘要
目的 探讨孕前体质指数（body mass index,BMI）及孕期体育活动与妊娠期糖尿病的关系。方法 将2012年3月～2014年12月在山西医科大学第一医院产科分娩的6211例单胎孕妇作为研究对象,根据孕前BMI和体育活动分组,采用非条件Logistic回归分析妊娠期糖尿病发生的影响因素。结果 6211例孕妇妊娠期糖尿病（gestational diabetes mellitus,GDM）的发生率为16.02%（995/6211）。孕前超重和肥胖者GDM发生率高于孕前BMI正常范围的孕妇（OR=2.288,95%CI：1.946～2.691）;孕前BMI较低者GDM的发生率低于孕前BMI正常范围的孕妇（OR=0.692,95%CI：0.541～0.885）;未发现体育活动与妊娠期糖尿病有关。孕前BMI与孕期体育活动间不存在交互作用（OR=0.899,95%CI：0.370～1.534）。结论 孕前超重和肥胖是GDM发生的危险因素,因此孕妇应合理地控制孕前BMI以减少妊娠期糖尿病的发生。
Objective The study aims to investigate the relationship between maternal prepregnancy body mass in- dex（BMI） , physical activity during pregnancy and the gestational diabetes mellitus （GDM）. Methods A birth cohort study,which including 6 211 pregnant women with single birth, was conducted from March 2012 to December 2014 in the First Affiliated Hospital of Shanxi Medical University. Information on birth outcomes and maternal complications were ab- stracted from medical records. Multivariate unconditional logistic regression models were employed to estimate the associa- tions between pre-pregnancy BMI and GDM. Results A total of 16.02% （995/6 211 ） women were diagnosed with GDM. The risk of GDM in obese and overweight pregnant women was higher than that in normal BMI pregnant women （ OR = 2. 288,95% CI：I. 946-2. 691 ） , but the risk of GDM in underweight pregnant women was lower （ OR =0. 692,95% CI ： 0. 541-0. 885）. The association between physical activity during pregnancy and the risk of GDM had not been found. We also did not observe significant interactions between pre-pregnancy BMI and physical activity during pregnancy （ OR = 0. 899,95% CI：0. 370-1. 534）. Conclusions High pre-pregnancy BMI may be a risk factor of GDM, and keeping normal pre-pregnancy BM1 is a better way to prevent GDM.
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2016年第4期362-365,共4页
Chinese Journal of Disease Control & Prevention
基金
国家自然科学基金(81473061)
山西医科大学十人计划项目(2015年)
山西省青年科技研究基金(2013021033-2)
