摘要
目的:探讨布地奈德配合盐酸氨溴索实行雾化吸入治疗支气管肺炎患儿的临床疗效。方法:选择汉川市人民医院2013年2月—2015年1月期间收治的188例支气管炎患儿作为研究对象,按随机数字表法分为观察组与对照组,每组各94例。对照组患儿使用布地奈德气雾剂对患儿实行雾化治疗,观察组患儿在对照组的根本上配合盐酸氨溴索雾化吸入。观察2组患儿的总有效率、症状消失与住院时间。结果:通过治疗,观察组患儿的总有效率为96.81%(91/94),显著高于对照组的87.23%(82/94),差异有统计学意义(P<0.05);观察组患儿症状消失与住院的时间显著低于对照组,差异有统计学意义(P<0.01)。2组患儿不良反应发生情况比较,差异有统计学意义(P<0.05)。结论:使用布地奈德配合盐酸氨溴索药物对患有支气管肺炎的患儿实行雾化吸入,效果理想,可缩短治疗的时间,安全可靠,值得临床推广。
OBJECTIVE： To probe into the clinical efficacy of budesonide combined with ambroxol hydrochloride inhalation in treatment of children with bronchial pneumonia. METHODS： 188 cases of children with bronchial pneumonia admitted into Hanchuan People＇s Hospital from Feb. 2013 to Jan. 2015 were selected to be divided into observation group and control group via the random number table,with 94 cases in each. The control group were treated with the budesonide aerosol,while the control group additionally received ambroxol hydrochloride inhalation based on the control group. The total effective rate,disappearance time of symptoms and length of stay in two group of patients were observed and compared. RESULTS： After treatment,the total effective rate of of observation group was96. 81%（ 91 /94）,significantly higher than that of control group 87. 23%（ 82 /94）,with statistically significant difference（ P〈0. 05）. Yet the disappearance time of symptoms and length of stay in observation group was significantly lower than that in control group,the difference was extremely significant（ P〈0. 01）. There were statistically significant differences of adverse drug reactions between two group of patients（ P〈0. 05）.CONCLUSIONS： Not only the efficacy of budesonide combined with ambroxol hydrochloride inhalation in treatment of children with bronchial pneumonia is significant,but can shorten the treatment time,with safe and reliable effects. It is worthy of clinical application and promotion.
出处
《中国医院用药评价与分析》
2016年第3期336-338,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
雾化吸入
布地奈德
盐酸氨溴索
小儿支气管炎
Atomization inhalation
Budesonide
Ambroxol hydrochloride
Children with bronchial pneumonia
