摘要
目的探讨阴道彩色多普勒超声结合血清糖类抗原-125(CA_(125))、孕酮(P)、雌二醇(E_2)、β-绒毛膜促性腺激素(β-HCG)水平检测对先兆流产的临床意义。方法选取在我院进行孕检的80例先兆流产孕妇为先兆流产组,80例正常妊娠体检孕妇为正常组,采用阴道彩色多普勒超声进行检查黄体血流动力学指标峰值流速(PSV)、阻力指数(RI),电化学发光免疫法测定血清CA_(125)、P、E_2、β-HCG水平,分析其对先兆流产的临床意义。结果先兆流产组PSV明显小于正常组,RI明显大于正常组,差异有统计学意义(P<0.05),先兆流产组CA_(125)水平高于正常组,P、E_2、β-HCG水平低于正常组,差异有统计学意义(P<0.05)。结论阴道彩色多普勒超声联合血清CA_(125)、P、E_2、β-HCG水平检测,对早期诊断先兆流产具有重要临床价值,可提高对先兆流产孕妇预后预测的准确性。
Objective To explore the clinical significance of transvaginal color Doppler ultrasound in combined with detection of serum CA_（125）,P,E_2,and β-HCG levels in predicting the threatened abortion. Methods A total of 80 pregnant women with threatened abortion were served as the threatened abortion group,while 80 cases with normal pregnancy were served as the normal group. The transvaginal color Doppler ultrasound was used to examine PSV and RI,the electrochemiluminescence immunoassay was used to detect the levels of serum CA_（125）,P,E_2,and β-HCG,and their clinical significance to the threatened abortion was analyzed. Results PSV in the threatened group was significantly less than that in the normal group,while RI was significantly greater than that in the control group（ P〈0. 05）.CA_（125） level in the threatened group was significantly higher than that in the normal group,while P,E_2,and β-HCG levels were significantly lower than those in the normal group（ P〈0. 05）. Conclusion Application of transvaginal color Doppler ultrasound in combined with detection of serum CA_（125）,P,E_2,and β-HCG levels is of great clinical value in the early diagnosis of threatened abortion,and can enhance the accuracy of predicting the prognosis of threatened abortion.
出处
《长春中医药大学学报》
2016年第2期399-400,共2页
Journal of Changchun University of Chinese Medicine
基金
河北省科学计划支撑项目(20130291)
